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Type-II Collagen and Hyaluronic Acid: study protocols

5 study groups took Type-II Collagen together with Hyaluronic Acid. These are the doses the studies gave. They are not a recommendation.

Type-II Collagen: what the research found →

Dose per serving from research: Type-II Collagen

5 study groups in 5 studies say how much Type-II Collagen participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 40% of 5 study groups.

Daily doseStudy groups
25 mg to 50 mg
2
50 mg to 100 mg
1
100 mg to 250 mg
0
250 mg to 500 mg
1
500 mg to 1 g
1

Commonly used together

5 of 5 study groups took Type-II Collagen and Hyaluronic Acid with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Collagen
4
Vitamin C
4

5 study groups

Study
Novel Hydrolyzed Chicken Sternal Cartilage Extract Improves Facial Epidermis and Connective Tissue in Healthy Adult Females: A Randomized, Double-Blind, Placebo-Controlled Trial
2019 · intervention · Females aged 39–59 years described as healthy adults
600 mg100 mg12 weeks—
Effects of cartilage-supporting nutritional supplementation on knee osteoarthritis symptoms and quality of life in a 12-week randomized double-blind placebo-controlled pilot study
2025 · Verum · Adults with mild-to-moderate knee osteoarthritis and slight-to-moderate knee pain; mean age 62.7 years; women and men
60 mg—12 weeks36
A Dietary Supplement in the Management of Patients with Lumbar Osteochondrosis: A Randomized, Double-Blinded, Placebo-Controlled Study
2024 · supplement group · Adults with symptomatic MRI-confirmed lumbar osteochondrosis; age range and sex not specified
360 mg60 mg90 days26
Effect of supplementation with type 1 and type 3 collagen peptide and type 2 hydrolyzed collagen on osteoarthritis-related pain, quality of life, and physical function: A double-blind, randomized, placebo-controlled study
2025 · Collagen · Adults aged 35–65 with unilateral Kellgren-Lawrence grade 2–3 knee osteoarthritis
40 mg100 mg8 weeks16
The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy: a randomized, double-blind, placebo-controlled study
2025 · collagen group · men and women aged 35–65 with grade 1 or 2 meniscal tears
40 mg100 mg8 weeks17
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