Thiamine, Zinc, Vitamin B6 and Vitamin B12: study protocols
6 study groups took Thiamine together with Zinc, Vitamin B6 and Vitamin B12. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Thiamine
6 study groups in 6 studies say how much Thiamine participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 mg to 2.5 mg, 50% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 500 mcg or less | 1 |
| 500 mcg to 1 mg | 0 |
| 1 mg to 2.5 mg | 3 |
| 2.5 mg to 5 mg | 0 |
| 5 mg to 10 mg | 2 |
Dose per serving from research: Zinc
6 study groups in 6 studies say how much Zinc participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 10 mg to 25 mg, 50% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg or less | 1 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 3 |
| 25 mg to 50 mg | 1 |
Dose per serving from research: Vitamin B6
6 study groups in 6 studies say how much Vitamin B6 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 mg to 2.5 mg, 33% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 500 mcg or less | 1 |
| 500 mcg to 1 mg | 1 |
| 1 mg to 2.5 mg | 2 |
| 2.5 mg to 5 mg | 1 |
| 5 mg to 10 mg | 1 |
Dose per serving from research: Vitamin B12
6 study groups in 6 studies say how much Vitamin B12 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 2.5 mcg to 5 mcg and 5 mcg to 10 mcg, 33% of 6 study groups each.
| Daily dose | Study groups |
|---|---|
| 1 mcg or less | 1 |
| 1 mcg to 2.5 mcg | 1 |
| 2.5 mcg to 5 mcg | 2 |
| 5 mcg to 10 mcg | 2 |
Commonly used together
6 of 6 study groups took Thiamine, Zinc, Vitamin B6 and Vitamin B12 with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Riboflavin | 5 |
| Vitamin E | 5 |
| Niacin | 4 |
| Vitamin A | 4 |
| Copper | 3 |
| Folic Acid | 3 |
| Iron | 3 |
| Vitamin C | 3 |
| Vitamin D | 3 |
6 study groups
| Study | ||||||
|---|---|---|---|---|---|---|
| Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren 2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified | 1.4 mg | 20 mg | 1.7 mg | 2 mcg | 335 days | — |
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 1.6 mg | 30 mg | 2.2 mg | 2.6 mcg | — | — |
| Effect of zinc plus multivitamin supplementation on growth in school children 2016 · Chelated zinc plus multivitamins · Healthy Thai schoolchildren aged 4–13 years | 10 mg | 20 mg | 1 mg | 10 mcg | 26 weeks | 70 |
| Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy 2024 · 10-element combination tablet · Overweight or obese adults with type 2 diabetes and mild-to-moderate painful diabetic neuropathy; mean age 63 years | 2.2 mg | 5 mg | 3 mg | 5 mcg | 26 weeks | 36 |
| Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation 2011 · Group MVB · Patients with type 2 diabetes | 10 mg | 20 mg | 10 mg | 10 mcg | 120 days | — |
| Daily supplementation of a multiple micronutrient powder improves folate but not thiamine, riboflavin, or vitamin B(12) status among young Laotian children: a randomized controlled trial 2022 · micronutrient powder group (MNP) · Children aged 6–23 months in rural Lao PDR; no disease-based selection, with high prevalence of undernutrition and micronutrient deficiencies | 500 mcg | 10 mg | 500 mcg | 0.9 mcg | 36 weeks | 130 |