Thiamine, Vitamin E, Vitamin B6, Vitamin B12 and Riboflavin: study protocols
7 study groups took Thiamine together with Vitamin E, Vitamin B6, Vitamin B12 and Riboflavin. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Thiamine
7 study groups in 6 studies say how much Thiamine participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 mg to 2.5 mg and 10 mg to 25 mg, 29% of 7 study groups each.
| Daily dose | Study groups |
|---|---|
| 500 mcg or less | 1 |
| 500 mcg to 1 mg | 0 |
| 1 mg to 2.5 mg | 2 |
| 2.5 mg to 5 mg | 0 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 2 |
| 25 mg to 50 mg | 1 |
Dose per serving from research: Vitamin E
7 study groups in 6 studies say how much Vitamin E participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 mg to 10 mg and 25 mg to 50 mg, 29% of 7 study groups each.
| Daily dose | Study groups |
|---|---|
| 5 mg or less | 1 |
| 5 mg to 10 mg | 2 |
| 10 mg to 25 mg | 1 |
| 25 mg to 50 mg | 2 |
| 50 mg to 100 mg | 1 |
Dose per serving from research: Vitamin B6
7 study groups in 6 studies say how much Vitamin B6 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 mg to 2.5 mg and 10 mg to 25 mg, 29% of 7 study groups each.
| Daily dose | Study groups |
|---|---|
| 500 mcg or less | 1 |
| 500 mcg to 1 mg | 0 |
| 1 mg to 2.5 mg | 2 |
| 2.5 mg to 5 mg | 0 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 2 |
| 25 mg to 50 mg | 1 |
Dose per serving from research: Vitamin B12
7 study groups in 6 studies say how much Vitamin B12 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 mcg to 50 mcg, 29% of 7 study groups.
| Daily dose | Study groups |
|---|---|
| 1 mcg or less | 1 |
| 1 mcg to 2.5 mcg | 1 |
| 2.5 mcg to 5 mcg | 1 |
| 5 mcg to 10 mcg | 1 |
| 10 mcg to 25 mcg | 0 |
| 25 mcg to 50 mcg | 2 |
| 50 mcg to 100 mcg | 0 |
| 100 mcg to 250 mcg | 0 |
| 250 mcg to 500 mcg | 0 |
| 500 mcg to 1 mg | 1 |
Dose per serving from research: Riboflavin
7 study groups in 6 studies say how much Riboflavin participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 mg to 2.5 mg and 5 mg to 10 mg and 10 mg to 25 mg, 29% of 7 study groups each.
| Daily dose | Study groups |
|---|---|
| 500 mcg or less | 1 |
| 500 mcg to 1 mg | 0 |
| 1 mg to 2.5 mg | 2 |
| 2.5 mg to 5 mg | 0 |
| 5 mg to 10 mg | 2 |
| 10 mg to 25 mg | 2 |
Commonly used together
7 of 7 study groups took Thiamine, Vitamin E, Vitamin B6, Vitamin B12 and Riboflavin with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Folic Acid | 5 |
| Vitamin C | 5 |
| Vitamin A | 4 |
| Zinc | 4 |
| Copper | 3 |
| Iron | 3 |
| Niacin | 3 |
7 study groups
| Study | |||||||
|---|---|---|---|---|---|---|---|
| Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren 2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified | 1.4 mg | 8 mg | 1.7 mg | 2 mcg | 1.6 mg | 335 days | — |
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 1.6 mg | 10 mg | 2.2 mg | 2.6 mcg | 1.8 mg | — | — |
| Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension 2005 · Multivitamin plus vitamin A · HIV-positive pregnant Tanzanian women | 20 mg | 30 mg | 25 mg | 50 mcg | 20 mg | — | — |
| Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension 2005 · Multivitamin without vitamin A · HIV-positive pregnant Tanzanian women | 20 mg | 30 mg | 25 mg | 50 mcg | 20 mg | — | — |
| A functional evaluation of anti-fatigue and exercise performance improvement following vitamin B complex supplementation in healthy humans, a randomized double-blind trial 2023 · Ex PLUS® group · Healthy male and female non-athletes aged 20–30 | 33.6 mg | 16.8 mg | 50 mg | 750 mcg | 10 mg | 4 weeks | 32 |
| Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation 2011 · Group MVB · Patients with type 2 diabetes | 10 mg | 100 mg | 10 mg | 10 mcg | 10 mg | 120 days | — |
| Daily supplementation of a multiple micronutrient powder improves folate but not thiamine, riboflavin, or vitamin B(12) status among young Laotian children: a randomized controlled trial 2022 · micronutrient powder group (MNP) · Children aged 6–23 months in rural Lao PDR; no disease-based selection, with high prevalence of undernutrition and micronutrient deficiencies | 500 mcg | 5 mg | 500 mcg | 0.9 mcg | 500 mcg | 36 weeks | 130 |