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Thiamine, Vitamin B6 and Folic Acid: study protocols

5 study groups took Thiamine together with Vitamin B6 and Folic Acid. These are the doses the studies gave. They are not a recommendation.

Thiamine: what the research found →

Dose per serving from research: Thiamine

5 study groups in 4 studies say how much Thiamine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 40% of 5 study groups.

Daily doseStudy groups
500 mcg or less
1
500 mcg to 1 mg
1
1 mg to 2.5 mg
1
2.5 mg to 5 mg
0
5 mg to 10 mg
0
10 mg to 25 mg
2

Dose per serving from research: Vitamin B6

5 study groups in 4 studies say how much Vitamin B6 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 40% of 5 study groups.

Daily doseStudy groups
500 mcg or less
1
500 mcg to 1 mg
1
1 mg to 2.5 mg
1
2.5 mg to 5 mg
0
5 mg to 10 mg
0
10 mg to 25 mg
2

Dose per serving from research: Folic Acid

5 study groups in 4 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mcg to 250 mcg and 500 mcg to 1 mg, 40% of 5 study groups each.

Daily doseStudy groups
100 mcg to 250 mcg
2
250 mcg to 500 mcg
1
500 mcg to 1 mg
2

Commonly used together

5 of 5 study groups took Thiamine, Vitamin B6 and Folic Acid with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Riboflavin
4
Vitamin B12
4
Vitamin E
4
Vitamin A
3

5 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
1.6 mg2.2 mg400 mcg——
Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension
2005 · Multivitamin plus vitamin A · HIV-positive pregnant Tanzanian women
20 mg25 mg800 mcg——
Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension
2005 · Multivitamin without vitamin A · HIV-positive pregnant Tanzanian women
20 mg25 mg800 mcg——
Effects of a food supplement containing phosphatidylserine on cognitive function in Chinese older adults with mild cognitive impairment: A randomized double-blind, placebo-controlled trial
2025 · intervention group · Chinese adults with mild cognitive impairment; mean age 67.95 years; 70 male and 120 female
960 mcg960 mcg180 mcg1 year95
Daily supplementation of a multiple micronutrient powder improves folate but not thiamine, riboflavin, or vitamin B(12) status among young Laotian children: a randomized controlled trial
2022 · micronutrient powder group (MNP) · Children aged 6–23 months in rural Lao PDR; no disease-based selection, with high prevalence of undernutrition and micronutrient deficiencies
500 mcg500 mcg150 mcg36 weeks130