Thiamine, Folic Acid, Vitamin B12, Vitamin E and Riboflavin: study protocols
5 study groups took Thiamine together with Folic Acid, Vitamin B12, Vitamin E and Riboflavin. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Thiamine
5 study groups in 4 studies say how much Thiamine participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 10 mg to 25 mg, 40% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 500 mcg or less | 1 |
| 500 mcg to 1 mg | 0 |
| 1 mg to 2.5 mg | 1 |
| 2.5 mg to 5 mg | 0 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 2 |
Dose per serving from research: Folic Acid
5 study groups in 4 studies say how much Folic Acid participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 500 mcg to 1 mg, 60% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 100 mcg to 250 mcg | 1 |
| 250 mcg to 500 mcg | 1 |
| 500 mcg to 1 mg | 3 |
Dose per serving from research: Vitamin B12
5 study groups in 4 studies say how much Vitamin B12 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 mcg to 50 mcg, 40% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 1 mcg or less | 1 |
| 1 mcg to 2.5 mcg | 0 |
| 2.5 mcg to 5 mcg | 1 |
| 5 mcg to 10 mcg | 1 |
| 10 mcg to 25 mcg | 0 |
| 25 mcg to 50 mcg | 2 |
Dose per serving from research: Vitamin E
5 study groups in 4 studies say how much Vitamin E participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 mg to 50 mg, 40% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg or less | 1 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 2 |
| 50 mg to 100 mg | 1 |
Dose per serving from research: Riboflavin
5 study groups in 4 studies say how much Riboflavin participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 10 mg to 25 mg, 40% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 500 mcg or less | 1 |
| 500 mcg to 1 mg | 0 |
| 1 mg to 2.5 mg | 1 |
| 2.5 mg to 5 mg | 0 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 2 |
Commonly used together
5 of 5 study groups took Thiamine, Folic Acid, Vitamin B12, Vitamin E and Riboflavin with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Vitamin B6 | 5 |
| Vitamin C | 4 |
| Vitamin A | 3 |
| Zinc | 3 |
5 study groups
| Study | |||||||
|---|---|---|---|---|---|---|---|
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 1.6 mg | 400 mcg | 2.6 mcg | 10 mg | 1.8 mg | — | — |
| Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension 2005 · Multivitamin plus vitamin A · HIV-positive pregnant Tanzanian women | 20 mg | 800 mcg | 50 mcg | 30 mg | 20 mg | — | — |
| Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension 2005 · Multivitamin without vitamin A · HIV-positive pregnant Tanzanian women | 20 mg | 800 mcg | 50 mcg | 30 mg | 20 mg | — | — |
| Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation 2011 · Group MVB · Patients with type 2 diabetes | 10 mg | 1 mg | 10 mcg | 100 mg | 10 mg | 120 days | — |
| Daily supplementation of a multiple micronutrient powder improves folate but not thiamine, riboflavin, or vitamin B(12) status among young Laotian children: a randomized controlled trial 2022 · micronutrient powder group (MNP) · Children aged 6–23 months in rural Lao PDR; no disease-based selection, with high prevalence of undernutrition and micronutrient deficiencies | 500 mcg | 150 mcg | 0.9 mcg | 5 mg | 500 mcg | 36 weeks | 130 |