Selenium and Folic Acid: study protocols
8 study groups took Selenium together with Folic Acid. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Selenium
8 study groups in 6 studies say how much Selenium participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 50 mcg to 100 mcg, 63% of 8 study groups.
| Daily dose | Study groups |
|---|---|
| 50 mcg or less | 1 |
| 50 mcg to 100 mcg | 5 |
| 100 mcg to 250 mcg | 2 |
Dose per serving from research: Folic Acid
8 study groups in 6 studies say how much Folic Acid participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 50 mcg to 100 mcg and 250 mcg to 500 mcg and 500 mcg to 1 mg and 1 mg to 2.5 mg, 25% of 8 study groups each.
| Daily dose | Study groups |
|---|---|
| 50 mcg to 100 mcg | 2 |
| 100 mcg to 250 mcg | 0 |
| 250 mcg to 500 mcg | 2 |
| 500 mcg to 1 mg | 2 |
| 1 mg to 2.5 mg | 2 |
Commonly used together
8 of 8 study groups took Selenium and Folic Acid with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Vitamin B12 | 4 |
| Vitamin E | 4 |
8 study groups
| Study | ||||
|---|---|---|---|---|
| A trial of the effect of micronutrient supplementation on treatment outcome, T cell counts, morbidity, and mortality in adults with pulmonary tuberculosis 2008 · micronutrients · Adults aged 18–65 with pulmonary tuberculosis, including HIV-positive and HIV-negative participants | 100 mcg | 800 mcg | 187 weeks | 443 |
| Randomized, double-blind, placebo-controlled trial of selenium supplements among HIV-infected pregnant women in Tanzania: effects on maternal and child outcomes 2008 · selenium group · Infants born to women with HIV in the selenium group; follow-up after birth | 200 mcg | 1.05 mg | — | — |
| Supportive treatment of vascular dysfunction in pediatric subjects with obesity: the OBELIX study 2022 · Treatment group · Children aged 6–17 years with obesity (BMI above the 95th percentile for age) | 55 mcg | 90 mcg | 26 weeks | 16 |
| Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease 2015 · Active group (RCT1, RCT2 and RCT3) · Men and women aged 50 years or older with mild or mild-to-moderate Alzheimer's disease; RCT3 participants were on stable approved Alzheimer's medication, while RCT1 and RCT2 participants were drug-free for Alzheimer's medication. | 60 mcg | 400 mcg | 24 weeks | 501 |
| Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease 2015 · Active product during open-label extension (OLE) · Men and women aged 50 years or older with mild Alzheimer's disease who completed RCT2. | 60 mcg | 400 mcg | 24 weeks | 201 |
| Randomized, double-blind, placebo-controlled trial of selenium supplements among HIV-infected pregnant women in Tanzania: effects on maternal and child outcomes 2008 · selenium group · Pregnant women aged about 27.5 years on average, at 12–27 weeks of gestation, living with HIV in Dar es Salaam, Tanzania | 200 mcg | 1.05 mg | — | 456 |
| The impact of a standardized micronutrient supplementation on PCOS-typical parameters: a randomized controlled trial 2019 · Multinutrient supplementation group · Women aged 19–35 with polycystic ovary syndrome (PCOS) | 70 mcg | 800 mcg | 90 days | 30 |
| Prophylactic iron supplementation in pregnant women in Norway 2001 · 15 mg iron daily · Non-anaemic pregnant women, allocated at about 10 weeks of pregnancy | 50 mcg | 100 mcg | — | — |