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Red Clover: study protocols

28 study groups say how much Red Clover participants took a day. These are the doses the studies gave. They are not a recommendation.

Red Clover: what the research found →

Dose per serving from products

98 products in our catalogue print how much Red Clover a serving holds.

Most common: 50 mg to 100 mg, 26% of 98 products.

Dose per servingProducts
25 mg or less
5
25 mg to 50 mg
18
50 mg to 100 mg
25
100 mg to 250 mg
15
250 mg to 500 mg
15
500 mg to 1 g
20

Dose per serving from research

27 study groups in 21 studies say how much Red Clover participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg to 100 mg, 63% of 27 study groups.

Daily doseStudy groups
25 mg to 50 mg
8
50 mg to 100 mg
17
100 mg to 250 mg
0
250 mg to 500 mg
0
500 mg to 1 g
1
over 1 g
1

Commonly used together

4 of 28 study groups took Red Clover with something else, but nothing that 3 or more different studies gave.

28 study groups

Study
Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts
2010 · Group A: MF11RCE · Postmenopausal women aged 40 or more
80 mg90 days109
The effect of red clover isoflavones on menopausal symptoms, lipids and vaginal cytology in menopausal women: a randomized, double-blind, placebo-controlled study
2005 · red clover isoflavone supplement · Postmenopausal women aged over 40 years, not using hormone therapy, with a Kupperman index score of at least 15
80 mg90 days60
Isoflavones obtained from red clover improve both dyslipidemia and menopausal symptoms in menopausal women: a prospective randomized placebo-controlled trial
2024 · red clover group · Postmenopausal women with dyslipidemia
80 mg26 weeks39
Isoflavones from red clover (Promensil) significantly reduce menopausal hot flush symptoms compared with placebo
2002 · isoflavones group · Postmenopausal women with more than 12 months of amenorrhoea and more than five hot flushes per day
80 mg12 weeks—
The effect of red clover isoflavone supplementation over vasomotor and menopausal symptoms in postmenopausal women
2012 · Group A red clover phase · Postmenopausal women aged 40 or more
80 mg90 days—
Effectiveness of red clover in alleviating menopausal symptoms: a 12-week randomized, controlled trial
2015 · intervention group · healthy postmenopausal women
40 mg12 weeks—
Nonhormonal management of postmenopausal women: effects of a red clover based isoflavones supplementation on climacteric syndrome and cardiovascular risk serum profile
2013 · phytoestrogens tablets · healthy postmenopausal women
60.8 mg26 weeks75
Combined Red Clover isoflavones and probiotics potently reduce menopausal vasomotor symptoms
2017 · RC (red clover extract) group · Perimenopausal women aged 40–65 with menopause symptoms, including at least 5 hot flushes per day
150 mL12 weeks30
A biochanin-enriched isoflavone from red clover lowers LDL cholesterol in men
2004 · biochanin-enriched red clover isoflavones · Middle-aged men and postmenopausal women; free-living volunteers
40 mg6 weeks40
A biochanin-enriched isoflavone from red clover lowers LDL cholesterol in men
2004 · formononetin-enriched red clover isoflavones · Middle-aged men and postmenopausal women; free-living volunteers
40 mg6 weeks40
Effects of dietary supplementation with isoflavones from red clover on ambulatory blood pressure and endothelial function in postmenopausal type 2 diabetes
2003 · red clover isoflavone supplementation · postmenopausal women with type 2 diabetes
50 mg4 weeks16
The effects of phytoestrogen isoflavones on bone density in women: a double-blind, randomized, placebo-controlled trial
2004 · red clover-derived isoflavone supplement · Women aged 49–65 years; menopausal status varied
43.5 mg1 year—
Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial
2017 · RCE · Postmenopausal women with osteopenia; age range not stated
60 mg1 year—
Urinary isoflavonoid excretion is inversely associated with the ratio of protein to dietary fibre intake in young women
2005 · Study 1 isoflavone supplement · Healthy premenopausal women
86 mg60 days14
Urinary isoflavonoid excretion is inversely associated with the ratio of protein to dietary fibre intake in young women
2005 · Study 2 isoflavone supplement · Healthy premenopausal women
86 mg90 days11
Effect of Trifolium pratense-derived isoflavones on the lipid profile of postmenopausal women with increased body mass index
2008 · T. pratense isoflavones · Postmenopausal women aged over 40 years who were not using hormone therapy; BMI subgroups included women with BMI ≥25 kg/m² and BMI <25 kg/m²
80 mg90 days60
Effect of red clover-derived isoflavone supplementation on insulin-like growth factor, lipid and antioxidant status in healthy female volunteers: a pilot study
2004 · isoflavone phase · Healthy premenopausal and postmenopausal women
86 mg30 days23
The effect of isoflavones extracted from red clover (Rimostil) on lipid and bone metabolism
2001 · 28.5 mg phytoestrogens daily · Postmenopausal women
28.5 mg26 weeks—
The effect of isoflavones extracted from red clover (Rimostil) on lipid and bone metabolism
2001 · 57 mg phytoestrogens daily · Postmenopausal women
57 mg26 weeks—
The effect of isoflavones extracted from red clover (Rimostil) on lipid and bone metabolism
2001 · 85.5 mg phytoestrogens daily · Postmenopausal women
85.5 mg26 weeks—
Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal women
2003 · biochanin-enriched isoflavones · Healthy men and women aged 45 to 75 years
80 mg6 weeks—
Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal women
2003 · formononetin-enriched isoflavones · Healthy men and women aged 45 to 75 years
80 mg6 weeks—
Modest protective effects of isoflavones from a red clover-derived dietary supplement on cardiovascular disease risk factors in perimenopausal women, and evidence of an interaction with ApoE genotype in 49-65 year-old women
2004 · isoflavone group · Women aged 49–65 years, including perimenopausal and postmenopausal women
43.5 mg1 year—
Effects of a red clover extract (MF11RCE) on endometrium and sex hormones in postmenopausal women
2006 · MF11RCE (verum) · Postmenopausal women aged 40 years or older
80 mg90 days—
Effect of oral phytoestrogen on androgenicity and insulin sensitivity in postmenopausal women
2012 · 40 mg oral phytoestrogen (Promensil)/day · Healthy, nondiabetic postmenopausal women; mean age 68 ± 7 years
40 mg90 days—
Effect of oral phytoestrogen on androgenicity and insulin sensitivity in postmenopausal women
2012 · 80 mg oral phytoestrogen (Promensil)/day · Healthy, nondiabetic postmenopausal women; mean age 68 ± 7 years
80 mg90 days—
Effects of isoflavone-rich red clover extract on blood glucose level: A randomized, double-blind, placebo-controlled trial
2021 · RC extract group · Participants aged 25 to 64 years; no specific condition stated
1.91 g8 weeks—
Polyphenol-Related Gut Metabotype Signatures Linked to Quality of Life in Postmenopausal Women: A Randomized, Placebo-Controlled Crossover Trial
2025 · Polyphenol-rich supplement (PPs) · Healthy postmenopausal women aged 45–59 with at least one climacteric symptom
750 mg8 weeks78