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All Prebiotics study protocols

Prebiotics and Probiotics: study protocols

9 study groups took Prebiotics together with Probiotics. These are the doses the studies gave. They are not a recommendation.

Prebiotics: what the research found →

Dose per serving from research: Prebiotics

9 study groups in 9 studies say how much Prebiotics participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mg to 1 g, 33% of 9 study groups.

Daily doseStudy groups
250 mg or less
1
250 mg to 500 mg
0
500 mg to 1 g
3
1 g to 2.5 g
2
2.5 g to 5 g
0
5 g to 10 g
2
10 g to 25 g
1

Dose per serving from research: Probiotics

5 study groups in 5 studies say how much Probiotics participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 billion CFU to 10 billion CFU and 10 billion CFU to 25 billion CFU, 40% of 5 study groups each.

Daily doseStudy groups
1 billion CFU or less
1
1 billion CFU to 2.5 billion CFU
0
2.5 billion CFU to 5 billion CFU
0
5 billion CFU to 10 billion CFU
2
10 billion CFU to 25 billion CFU
2

Commonly used together

None of these 9 study groups took Prebiotics and Probiotics with anything else.

9 study groups

Study
Effects of Bifidobacterium lactis HN019 and prebiotic oligosaccharide added to milk on iron status, anemia, and growth among children 1 to 4 years old
2010 · probiotic- and prebiotic-fortified milk · Children aged 1 to 4 years in a periurban community
2.4 g—1 year312
Prebiotic and probiotic fortified milk in prevention of morbidities among children: community-based, randomized, double-blind, controlled trial
2010 · Prebiotic and probiotic fortified milk (PP) · Children aged 1–4 years in a community setting in India, with no specific diagnosed condition required
2.4 g0.019 billion CFU1 year312
Synbiotics modulate gut microbiota and reduce enteritis and ventilator-associated pneumonia in patients with sepsis: a randomized controlled trial
2018 · Synbiotics group · Patients older than 16 years with sepsis requiring mechanical ventilation in the ICU
10 g3 g20 days35
Long-term safety and impact on infection rates of postnatal probiotic and prebiotic (synbiotic) treatment: randomized, double-blind, placebo-controlled trial
2008 · synbiotic group · Newborn infants at high risk for allergy
800 mg—26 weeks—
Perioperative synbiotics decrease postoperative complications in periampullary neoplasms: a randomized, double-blind clinical trial
2015 · group S (synbiotics) · Adults undergoing surgery for periampullary neoplasms; age and sex not specified
200 mg8 billion CFU2 weeks23
Effect of a Probiotic and a Synbiotic on Body Fat Mass, Body Weight and Traits of Metabolic Syndrome in Individuals with Abdominal Overweight: A Human, Double-Blind, Randomised, Controlled Clinical Study
2023 · Synbiotic · Adults aged 18 years or older, women and men with abdominal overweight or obesity (BMI ≥25 and elevated waist circumference)
10 g—12 weeks60
Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial
2023 · Group D · Adults aged 18–70 with functional constipation
960 mg19.2 billion CFU4 weeks50
Effects and Persistence of Bifidobacterium animalis subsp. lactis BL-99 and Fructooligosaccharides on Older Adults with Functional Constipation: A Randomized, Double-Blind, Placebo-Controlled Trial
2025 · synbiotic group · Adults aged 60 years or older with functional constipation by Rome IV criteria and no significant comorbidities
800 mg20 billion CFU4 weeks34
Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults-Randomized Controlled Trial
2016 · LU + B420 · Adults aged 18–65 with overweight or obesity (BMI 28.0–34.9)
12 g10 billion CFU26 weeks—
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