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Lemon Balm: study protocols

28 study groups say how much Lemon Balm participants took a day. These are the doses the studies gave. They are not a recommendation.

Lemon Balm: what the research found →

Dose per serving from products

226 products in our catalogue print how much Lemon Balm a serving holds.

Most common: 50 mg to 100 mg, 27% of 226 products.

Dose per servingProducts
1 mg or less
12
1 mg to 2.5 mg
0
2.5 mg to 5 mg
1
5 mg to 10 mg
9
10 mg to 25 mg
20
25 mg to 50 mg
32
50 mg to 100 mg
61
100 mg to 250 mg
48
250 mg to 500 mg
20
500 mg to 1 g
9
1 g to 2.5 g
14

Dose per serving from research

27 study groups in 16 studies say how much Lemon Balm participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mg to 1 g, 52% of 27 study groups.

Daily doseStudy groups
250 mg or less
1
250 mg to 500 mg
5
500 mg to 1 g
14
1 g to 2.5 g
3
2.5 g to 5 g
4

Commonly used together

None of these 28 study groups took Lemon Balm with anything else.

28 study groups

Study
Effects of a traditional herbal formula containing Melissa officinalis, Pimpinella anisum, and Rosa damascena on anxiety and depression in patients with constipation-predominant irritable bowel syndrome (IBS-C): A double-blind randomized clinical trial
2024 · herbal formula group · Adults aged 18–60 with constipation-predominant irritable bowel syndrome (IBS-C)
1 g4 weeks48
Effects of Melissa officinalis Phytosome on Sleep Quality: Results of a Prospective, Double-Blind, Placebo-Controlled, and Cross-Over Study
2024 · Melissa officinalis Phytosome (MOP) · Adults aged 18–65 with fatigue upon waking and unrefreshing sleep
200 mg2 weeks30
Anti-stress effects of lemon balm-containing foods
2014 · Study 1: 0.3 g lemon balm with natural fruit sweetener · Healthy men and women aged 18–39
300 mg1 day25
Anti-stress effects of lemon balm-containing foods
2014 · Study 1: 0.6 g lemon balm with natural fruit sweetener · Healthy men and women aged 18–39
600 mg1 day25
Anti-stress effects of lemon balm-containing foods
2014 · Study 1: 0.6 g lemon balm with artificial sweeteners · Healthy men and women aged 18–39
600 mg1 day25
The effects of melissa officinalis on depression and anxiety in type 2 diabetes patients with depression: a randomized double-blinded placebo-controlled clinical trial
2023 · M. officinalis (HEMO) group · Adults aged 20–65, both sexes, with type 2 diabetes and depressive symptoms
700 mg12 weeks23
Anti-stress effects of lemon balm-containing foods
2014 · Study 2: 0.3 g lemon balm with natural fruit sweetener · Healthy men and women aged 21–30
300 mg1 day21
Anti-stress effects of lemon balm-containing foods
2014 · Study 2: 0.6 g lemon balm with natural fruit sweetener · Healthy men and women aged 21–30
600 mg1 day21
Anti-stress effects of lemon balm-containing foods
2014 · Study 2: 0.6 g lemon balm with artificial sweeteners · Healthy men and women aged 21–30
600 mg1 day21
Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm)
2002 · 300 mg Melissa officinalis · healthy young adults; sex not stated
300 mg1 day20
Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm)
2002 · 600 mg Melissa officinalis · healthy young adults; sex not stated
600 mg1 day20
Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm)
2002 · 900 mg Melissa officinalis · healthy young adults; sex not stated
900 mg1 day20
Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties
2003 · 600 mg dried leaf · Healthy young adults
600 mg1 day20
Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties
2003 · 1000 mg dried leaf · Healthy young adults
1 g1 day20
Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties
2003 · 1600 mg dried leaf · Healthy young adults
1.6 g1 day20
Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm)
2004 · 300 mg lemon balm · healthy volunteers; age and sex not specified
300 mg1 day18
Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm)
2004 · 600 mg lemon balm · healthy volunteers; age and sex not specified
600 mg1 day18
A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression
2020 · Melissa officinalis (lemon balm; Group C) · Adults aged 18–65 with mild to moderate depression
2 g8 weeks15
Anti-stress effects of lemon balm-containing foods
2014 · Pilot study lemon balm extract · Five healthy men and women aged 23–28 who considered themselves to lead a stressed lifestyle
1.8 g1 day5
Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety
2015 · Melissa officinalis extract · Adults with benign heart palpitations
1 g2 weeks—
The effects of Melissa officinalis supplementation on depression, anxiety, stress, and sleep disorder in patients with chronic stable angina
2018 · MO supplement group · Patients with chronic stable angina; age and sex not specified
3 g8 weeks—
Melissa officinalis tea favourably affects the frequency of premature ventricular beats and cardiometabolic profile among patients with premature ventricular contraction: A randomised open-label controlled trial
2021 · Melissa officinalis tea group · Adults with a confirmed diagnosis of moderate to low-grade premature ventricular contractions; mean age 47 years and approximately 67.8% women
4 g12 weeks—
Effect of Melissa officinalis on systolic and diastolic blood pressures in essential hypertension: A double-blind crossover clinical trial
2021 · Melissa officinalis phase · Patients with essential hypertension; age and sex not reported
400 mg4 weeks49
Comparison of the effects of Echium amoenum and Melissa officinalis on hypertension in stage 1 hypertensive patients: A randomized, triple-blind, three-arm clinical trial
2025 · Melissa officinalis · Patients with stage 1 hypertension; age and sex not specified
10 mL4 weeks35
Lemon balm: A promising herbal therapy for patients with borderline hyperlipidemia-A randomized double-blind placebo-controlled clinical trial
2016 · MO group · Patients with borderline hyperlipidemia
3 g60 days—
The effects of Melissa officinalis (lemon balm) in chronic stable angina on serum biomarkers of oxidative stress, inflammation and lipid profile
2018 · oral MO · Patients with chronic stable angina; age range and sex not specified
3 g8 weeks40
Efficacy of Melissa officinalis L. (lemon balm) extract on glycemic control and cardiovascular risk factors in individuals with type 2 diabetes: A randomized, double-blind, clinical trial
2019 · M. officinalis group · Patients with type 2 diabetes; age and sex not stated
700 mg12 weeks31
Safety and efficacy of Melissa officinalis (lemon balm) on ApoA-I, Apo B, lipid ratio and ICAM-1 in type 2 diabetes patients: A randomized, double-blinded clinical trial
2018 · Melissa officinalis group · Patients aged 20–65 with type 2 diabetes
700 mg12 weeks—
Lemon Balm: study protocols | supp.fit