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Iron, Zinc, Vitamin A and Folic Acid: study protocols

21 study groups took Iron together with Zinc, Vitamin A and Folic Acid. These are the doses the studies gave. They are not a recommendation.

Iron: what the research found →

Dose per serving from research: Iron

21 study groups in 16 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 43% of 21 study groups.

Daily doseStudy groups
5 mg or less
1
5 mg to 10 mg
4
10 mg to 25 mg
2
25 mg to 50 mg
9
50 mg to 100 mg
5

Dose per serving from research: Zinc

21 study groups in 16 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 38% of 21 study groups.

Daily doseStudy groups
2.5 mg or less
1
2.5 mg to 5 mg
5
5 mg to 10 mg
2
10 mg to 25 mg
8
25 mg to 50 mg
5

Dose per serving from research: Vitamin A

20 study groups in 15 studies say how much Vitamin A participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg, 50% of 20 study groups.

Daily doseStudy groups
250 mcg or less
1
250 mcg to 500 mcg
7
500 mcg to 1 mg
10
1 mg to 2.5 mg
2

Dose per serving from research: Folic Acid

20 study groups in 15 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 55% of 20 study groups.

Daily doseStudy groups
100 mcg to 250 mcg
7
250 mcg to 500 mcg
11
500 mcg to 1 mg
2

Commonly used together

19 of 21 study groups took Iron, Zinc, Vitamin A and Folic Acid with something else. Shown: what 3 or more different studies gave. The 10 most common of 11.

What was given together, not what works together.

Taken withStudy groups
Vitamin C
16
Copper
13
Iodine
13
Selenium
13
Vitamin E
12
Vitamin D
11
Niacin
10
Vitamin B12
10
Vitamin B6
9
Riboflavin
6

21 study groups

Study
Impact of micronutrient supplementation during pregnancy on birth weight, duration of gestation, and perinatal mortality in rural western China: double blind cluster randomised controlled trial
2008 · Multiple micronutrients · Pregnant women resident in disadvantaged rural counties in Shaanxi Province, China; eligible women enrolled before 28 weeks’ gestation
30 mg15 mg800 mcg400 mcg—1,899
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · EMMS (early food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg15 mg800 mcg400 mcg——
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · UMMS (usual food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg15 mg800 mcg400 mcg——
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Folic acid + iron + zinc · Pregnant women in rural Nepal
60 mg30 mg1 mg400 mcg——
Predictors of adherence to micronutrient supplementation before and during pregnancy in Vietnam
2017 · MM (multiple micronutrients) preconception group · Women of reproductive age in Vietnam intending to become pregnant
8.57 mg2.14 mg114 mcg400 mcg54 weeks1,469
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-180 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg15 mg800 mcg400 mcg180 days516
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-90 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg15 mg800 mcg400 mcg180 days515
Associations of antenatal micronutrient supplementation with adolescent blood pressure: evidence from a 14-year follow-up study of a randomized controlled trial
2025 · Multiple micronutrients (MMNs; UNIMMAP formulation) · Pregnant women less than 28 weeks of gestation; offspring were followed up at ages 10–14 years
30 mg15 mg————
Iron status and inherited haemoglobin disorders modify the effects of micronutrient powders on linear growth and morbidity among young Lao children in a double-blind randomised trial
2019 · MNP group · Children aged 6–23 months in rural Lao PDR; young children, including children with anaemia and inherited haemoglobin disorders
6 mg10 mg400 mcg150 mcg36 weeks852
Effect of Micronutrient Powder (MNP) with a Low-Dose of Iron on Hemoglobin and Iron Biomarkers, and Its Effect on Morbidities in Rural Bangladeshi Children Drinking Groundwater with a High-Level of Iron: A Randomized Controlled Trial
2019 · low-dose-iron MNP · Bangladeshi children aged 2–5 years drinking groundwater with a high level of iron
5 mg5 mg300 mcg150 mcg60 days—