Iron, Vitamin D, Folic Acid, Vitamin B6 and Selenium: study protocols
7 study groups took Iron together with Vitamin D, Folic Acid, Vitamin B6 and Selenium. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Iron
7 study groups in 5 studies say how much Iron participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 mg to 50 mg, 86% of 7 study groups.
| Daily dose | Study groups |
|---|---|
| 10 mg or less | 1 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 6 |
Dose per serving from research: Vitamin D
5 study groups in 3 studies say how much Vitamin D participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 100 IU to 250 IU, 80% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 100 IU or less | 1 |
| 100 IU to 250 IU | 4 |
Dose per serving from research: Folic Acid
6 study groups in 4 studies say how much Folic Acid participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mcg to 500 mcg, 83% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 250 mcg to 500 mcg | 5 |
| 500 mcg to 1 mg | 1 |
Dose per serving from research: Vitamin B6
7 study groups in 5 studies say how much Vitamin B6 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 mg to 2.5 mg, 86% of 7 study groups.
| Daily dose | Study groups |
|---|---|
| 500 mcg or less | 1 |
| 500 mcg to 1 mg | 0 |
| 1 mg to 2.5 mg | 6 |
Dose per serving from research: Selenium
6 study groups in 4 studies say how much Selenium participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 50 mcg to 100 mcg, 83% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 10 mcg or less | 1 |
| 10 mcg to 25 mcg | 0 |
| 25 mcg to 50 mcg | 0 |
| 50 mcg to 100 mcg | 5 |
Commonly used together
7 of 7 study groups took Iron, Vitamin D, Folic Acid, Vitamin B6 and Selenium with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Copper | 7 |
| Iodine | 7 |
| Vitamin A | 7 |
| Vitamin B12 | 7 |
| Vitamin C | 7 |
| Vitamin E | 7 |
| Zinc | 7 |
| Niacin | 6 |
7 study groups
| Study | |||||||
|---|---|---|---|---|---|---|---|
| Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh 2014 · EMMS (early food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation | 30 mg | 200 IU | 400 mcg | 1.9 mg | 65 mcg | — | — |
| Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh 2014 · UMMS (usual food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation | 30 mg | 200 IU | 400 mcg | 1.9 mg | 65 mcg | — | — |
| Predictors of adherence to micronutrient supplementation before and during pregnancy in Vietnam 2017 · MM (multiple micronutrients) preconception group · Women of reproductive age in Vietnam intending to become pregnant | 8.57 mg | 85.7 IU | 400 mcg | 271 mcg | 9.29 mcg | 54 weeks | 1,469 |
| Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia 2025 · MMS-180 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy | 30 mg | 200 IU | 400 mcg | 1.9 mg | 65 mcg | 180 days | 516 |
| Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia 2025 · MMS-90 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy | 30 mg | 200 IU | 400 mcg | 1.9 mg | 65 mcg | 180 days | 515 |
| Associations of antenatal micronutrient supplementation with adolescent blood pressure: evidence from a 14-year follow-up study of a randomized controlled trial 2025 · Multiple micronutrients (MMNs; UNIMMAP formulation) · Pregnant women less than 28 weeks of gestation; offspring were followed up at ages 10–14 years | 30 mg | — | — | 1.9 mg | — | — | — |
| Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh 2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified | 27 mg | 5 mcg | 600 mcg | 1.9 mg | 60 mcg | — | 176 |