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Iron, Vitamin B6, Vitamin D, Vitamin B12 and Riboflavin: study protocols

7 study groups took Iron together with Vitamin B6, Vitamin D, Vitamin B12 and Riboflavin. These are the doses the studies gave. They are not a recommendation.

Iron: what the research found →

Dose per serving from research: Iron

7 study groups in 5 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg and 25 mg to 50 mg, 43% of 7 study groups each.

Daily doseStudy groups
5 mg to 10 mg
3
10 mg to 25 mg
1
25 mg to 50 mg
3

Dose per serving from research: Vitamin B6

7 study groups in 5 studies say how much Vitamin B6 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg, 71% of 7 study groups.

Daily doseStudy groups
500 mcg or less
1
500 mcg to 1 mg
0
1 mg to 2.5 mg
5
over 2.5 mg
1

Dose per serving from research: Vitamin B12

7 study groups in 5 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 43% of 7 study groups.

Daily doseStudy groups
0.5 mcg or less
1
0.5 mcg to 1 mcg
0
1 mcg to 2.5 mcg
2
2.5 mcg to 5 mcg
3
over 5 mcg
1

Dose per serving from research: Riboflavin

7 study groups in 5 studies say how much Riboflavin participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg, 86% of 7 study groups.

Daily doseStudy groups
500 mcg or less
1
500 mcg to 1 mg
0
1 mg to 2.5 mg
6

Commonly used together

7 of 7 study groups took Iron, Vitamin B6, Vitamin D, Vitamin B12 and Riboflavin with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Folic Acid
5
Iodine
4
Niacin
4
Thiamine
4
Vitamin A
4
Vitamin C
4
Vitamin E
4
Zinc
4

7 study groups

Study
Modifying effects of maternal Hb concentration on infant birth weight in women receiving prenatal iron-containing supplements: a randomised controlled trial
2016 · MMN group · Pregnant women aged at least 20 years, nulliparous, with Hb concentration ≥100 g/L and enrolled before 20 weeks of gestation
30 mg1.9 mg5 mcg2.6 mcg1.4 mg——
Predictors of adherence to micronutrient supplementation before and during pregnancy in Vietnam
2017 · MM (multiple micronutrients) preconception group · Women of reproductive age in Vietnam intending to become pregnant
8.57 mg271 mcg85.7 IU0.371 mcg200 mcg54 weeks1,469
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-180 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg1.9 mg200 IU2.6 mcg1.4 mg180 days516
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-90 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg1.9 mg200 IU2.6 mcg1.4 mg180 days515
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
12 mg2.6 mg10 mcg5.2 mcg1.8 mg—870
Fortified breakfast cereal consumed daily for 12 wk leads to a significant improvement in micronutrient intake and micronutrient status in adolescent girls: a randomised controlled trial
2016 · Fortified cereal, morning · Females aged 16–19 years who regularly skipped breakfast and had low riboflavin status and haemoglobin; no diagnosed illness
6.5 mg1.74 mg4.15 mcg1.45 mcg1.71 mg12 weeks18
Fortified breakfast cereal consumed daily for 12 wk leads to a significant improvement in micronutrient intake and micronutrient status in adolescent girls: a randomised controlled trial
2016 · Fortified cereal, evening · Females aged 16–19 years who regularly skipped breakfast and had low riboflavin status and haemoglobin; no diagnosed illness
6.5 mg1.74 mg4.15 mcg1.45 mcg1.71 mg12 weeks16