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All Iron study protocols

Iron, Selenium, Zinc, Folic Acid and Niacin: study protocols

16 study groups took Iron together with Selenium, Zinc, Folic Acid and Niacin. These are the doses the studies gave. They are not a recommendation.

Iron: what the research found →

Dose per serving from research: Iron

16 study groups in 13 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 56% of 16 study groups.

Daily doseStudy groups
5 mg to 10 mg
4
10 mg to 25 mg
1
25 mg to 50 mg
9
50 mg to 100 mg
2

Dose per serving from research: Selenium

15 study groups in 12 studies say how much Selenium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mcg to 100 mcg, 53% of 15 study groups.

Daily doseStudy groups
5 mcg to 10 mcg
2
10 mcg to 25 mcg
2
25 mcg to 50 mcg
0
50 mcg to 100 mcg
8
100 mcg to 250 mcg
3

Dose per serving from research: Zinc

16 study groups in 13 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 56% of 16 study groups.

Daily doseStudy groups
1 mg to 2.5 mg
2
2.5 mg to 5 mg
0
5 mg to 10 mg
2
10 mg to 25 mg
9
25 mg to 50 mg
3

Dose per serving from research: Folic Acid

15 study groups in 12 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 87% of 15 study groups.

Daily doseStudy groups
100 mcg to 250 mcg
2
250 mcg to 500 mcg
13

Dose per serving from research: Niacin

16 study groups in 13 studies say how much Niacin participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 56% of 16 study groups.

Daily doseStudy groups
2.5 mg to 5 mg
2
5 mg to 10 mg
2
10 mg to 25 mg
9
25 mg to 50 mg
3

Commonly used together

16 of 16 study groups took Iron, Selenium, Zinc, Folic Acid and Niacin with something else. Shown: what 3 or more different studies gave. The 10 most common of 13.

What was given together, not what works together.

Taken withStudy groups
Copper
16
Iodine
16
Vitamin A
16
Vitamin C
14
Vitamin D
14
Vitamin E
14
Vitamin B6
13
Vitamin B12
11
Riboflavin
8
vitamin B2
6

16 study groups

Study
Impact of micronutrient supplementation during pregnancy on birth weight, duration of gestation, and perinatal mortality in rural western China: double blind cluster randomised controlled trial
2008 · Multiple micronutrients · Pregnant women resident in disadvantaged rural counties in Shaanxi Province, China; eligible women enrolled before 28 weeks’ gestation
30 mg65 mcg15 mg400 mcg18 mg—1,899
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · EMMS (early food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg65 mcg15 mg400 mcg18 mg——
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · UMMS (usual food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg65 mcg15 mg400 mcg18 mg——
Predictors of adherence to micronutrient supplementation before and during pregnancy in Vietnam
2017 · MM (multiple micronutrients) preconception group · Women of reproductive age in Vietnam intending to become pregnant
8.57 mg9.29 mcg2.14 mg400 mcg2.57 mg54 weeks1,469
Effects of therapeutic zinc supplementation for diarrhea and two preventive zinc supplementation regimens on the incidence and duration of diarrhea and acute respiratory tract infections in rural Laotian children: A randomized controlled trial
2020 · MNP group · Children aged 6–23 months in rural Laos
6 mg17 mcg10 mg150 mcg6 mg40 weeks852
Effects of antenatal multiple micronutrient supplementation on children's weight and size at 2 years of age in Nepal: follow-up of a double-blind randomised controlled trial
2008 · intervention group · Pregnant women enrolled at no earlier than 12 weeks’ gestation, with singleton pregnancies and gestation up to 20 completed weeks
30 mg65 mcg15 mg400 mcg18 mg—600
Effect of antenatal multiple micronutrient supplementation on anthropometry and blood pressure in mid-childhood in Nepal: follow-up of a double-blind randomised controlled trial
2014 · intervention group (multiple micronutrient supplement) · Pregnant women attending antenatal care in Nepal; no specific age range or deficiency criterion stated
30 mg65 mcg15 mg400 mcg18 mg—600
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-180 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg65 mcg15 mg400 mcg18 mg180 days516
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-90 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg65 mcg15 mg400 mcg18 mg180 days515
Associations of antenatal micronutrient supplementation with adolescent blood pressure: evidence from a 14-year follow-up study of a randomized controlled trial
2025 · Multiple micronutrients (MMNs; UNIMMAP formulation) · Pregnant women less than 28 weeks of gestation; offspring were followed up at ages 10–14 years
30 mg—15 mg—18 mg——
Iron status and inherited haemoglobin disorders modify the effects of micronutrient powders on linear growth and morbidity among young Lao children in a double-blind randomised trial
2019 · MNP group · Children aged 6–23 months in rural Lao PDR; young children, including children with anaemia and inherited haemoglobin disorders
6 mg17 mcg10 mg150 mcg6 mg36 weeks852
Impact of Preconception Micronutrient Supplementation on Anemia and Iron Status during Pregnancy and Postpartum: A Randomized Controlled Trial in Rural Vietnam
2016 · Multiple micronutrients (MM) · Women aged 18–40 planning pregnancy in rural Vietnam; no specific diagnosed condition required
8.57 mg9.29 mcg2.14 mg400 mcg2.57 mg56 weeks508
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
60 mg130 mcg30 mg400 mcg36 mg184 days75
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · PE+MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
60 mg130 mcg30 mg400 mcg36 mg184 days75
Effects of prenatal micronutrient and early food supplementation on metabolic status of the offspring at 4.5 years of age. The MINIMat randomized trial in rural Bangladesh
2016 · MMS · Pregnant women in rural Bangladesh; offspring assessed at 4.5 years
30 mg65 mcg15 mg400 mcg18 mg—439
Maternal cortisol and stress are associated with birth outcomes, but are not affected by lipid-based nutrient supplements during pregnancy: an analysis of data from a randomized controlled trial in rural Malawi
2015 · MMN · Pregnant women aged 15–49 years in rural Malawi, enrolled at up to 20 weeks of gestation
20 mg130 mcg30 mg400 mcg36 mg—415
Iron, Selenium, Zinc, Folic Acid and Niacin: study protocols | supp.fit