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Iron, Selenium, Vitamin B12 and Niacin: study protocols

12 study groups took Iron together with Selenium, Vitamin B12 and Niacin. These are the doses the studies gave. They are not a recommendation.

Iron: what the research found →

Dose per serving from research: Iron

12 study groups in 10 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 67% of 12 study groups.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
2
25 mg to 50 mg
8

Dose per serving from research: Selenium

11 study groups in 9 studies say how much Selenium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mcg to 100 mcg, 64% of 11 study groups.

Daily doseStudy groups
5 mcg to 10 mcg
2
10 mcg to 25 mcg
0
25 mcg to 50 mcg
1
50 mcg to 100 mcg
7
over 100 mcg
1

Dose per serving from research: Vitamin B12

11 study groups in 9 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 64% of 11 study groups.

Daily doseStudy groups
0.25 mcg to 0.5 mcg
2
0.5 mcg to 1 mcg
0
1 mcg to 2.5 mcg
1
2.5 mcg to 5 mcg
7
over 5 mcg
1

Dose per serving from research: Niacin

12 study groups in 10 studies say how much Niacin participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 75% of 12 study groups.

Daily doseStudy groups
2.5 mg to 5 mg
2
5 mg to 10 mg
0
10 mg to 25 mg
9
25 mg to 50 mg
1

Commonly used together

12 of 12 study groups took Iron, Selenium, Vitamin B12 and Niacin with something else. Shown: what 3 or more different studies gave. The 10 most common of 13.

What was given together, not what works together.

Taken withStudy groups
Copper
12
Iodine
12
Vitamin A
12
Vitamin B6
12
Vitamin C
12
Vitamin D
12
Vitamin E
12
Zinc
12
Folic Acid
11
vitamin B2
6

12 study groups

Study
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · EMMS (early food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg65 mcg2.6 mcg18 mg——
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · UMMS (usual food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg65 mcg2.6 mcg18 mg——
Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren
2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified
18 mg40 mcg2 mcg16 mg335 days—
Predictors of adherence to micronutrient supplementation before and during pregnancy in Vietnam
2017 · MM (multiple micronutrients) preconception group · Women of reproductive age in Vietnam intending to become pregnant
8.57 mg9.29 mcg0.371 mcg2.57 mg54 weeks1,469
Effects of antenatal multiple micronutrient supplementation on children's weight and size at 2 years of age in Nepal: follow-up of a double-blind randomised controlled trial
2008 · intervention group · Pregnant women enrolled at no earlier than 12 weeks’ gestation, with singleton pregnancies and gestation up to 20 completed weeks
30 mg65 mcg2.6 mcg18 mg—600
Effect of antenatal multiple micronutrient supplementation on anthropometry and blood pressure in mid-childhood in Nepal: follow-up of a double-blind randomised controlled trial
2014 · intervention group (multiple micronutrient supplement) · Pregnant women attending antenatal care in Nepal; no specific age range or deficiency criterion stated
30 mg65 mcg2.6 mcg18 mg—600
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-180 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg65 mcg2.6 mcg18 mg180 days516
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-90 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg65 mcg2.6 mcg18 mg180 days515
Associations of antenatal micronutrient supplementation with adolescent blood pressure: evidence from a 14-year follow-up study of a randomized controlled trial
2025 · Multiple micronutrients (MMNs; UNIMMAP formulation) · Pregnant women less than 28 weeks of gestation; offspring were followed up at ages 10–14 years
30 mg——18 mg——
Impact of Preconception Micronutrient Supplementation on Anemia and Iron Status during Pregnancy and Postpartum: A Randomized Controlled Trial in Rural Vietnam
2016 · Multiple micronutrients (MM) · Women aged 18–40 planning pregnancy in rural Vietnam; no specific diagnosed condition required
8.57 mg9.29 mcg0.371 mcg2.57 mg56 weeks508
Effects of prenatal micronutrient and early food supplementation on metabolic status of the offspring at 4.5 years of age. The MINIMat randomized trial in rural Bangladesh
2016 · MMS · Pregnant women in rural Bangladesh; offspring assessed at 4.5 years
30 mg65 mcg2.6 mcg18 mg—439
Maternal cortisol and stress are associated with birth outcomes, but are not affected by lipid-based nutrient supplements during pregnancy: an analysis of data from a randomized controlled trial in rural Malawi
2015 · MMN · Pregnant women aged 15–49 years in rural Malawi, enrolled at up to 20 weeks of gestation
20 mg130 mcg5.2 mcg36 mg—415
Iron, Selenium, Vitamin B12 and Niacin: study protocols | supp.fit