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All Iron study protocols

Iron, Selenium, Vitamin A, Copper and Vitamin B12: study protocols

16 study groups took Iron together with Selenium, Vitamin A, Copper and Vitamin B12. These are the doses the studies gave. They are not a recommendation.

Iron: what the research found →

Dose per serving from research: Iron

16 study groups in 14 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 63% of 16 study groups.

Daily doseStudy groups
5 mg to 10 mg
3
10 mg to 25 mg
2
25 mg to 50 mg
10
over 50 mg
1

Dose per serving from research: Selenium

15 study groups in 13 studies say how much Selenium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mcg to 100 mcg, 67% of 15 study groups.

Daily doseStudy groups
5 mcg to 10 mcg
2
10 mcg to 25 mcg
1
25 mcg to 50 mcg
1
50 mcg to 100 mcg
10
over 100 mcg
1

Dose per serving from research: Vitamin A

14 study groups in 12 studies say how much Vitamin A participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg, 79% of 14 study groups.

Daily doseStudy groups
100 mcg to 250 mcg
2
250 mcg to 500 mcg
1
500 mcg to 1 mg
11

Dose per serving from research: Copper

16 study groups in 14 studies say how much Copper participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg, 63% of 16 study groups.

Daily doseStudy groups
250 mcg to 500 mcg
2
500 mcg to 1 mg
3
1 mg to 2.5 mg
10
over 2.5 mg
1

Dose per serving from research: Vitamin B12

15 study groups in 13 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 67% of 15 study groups.

Daily doseStudy groups
0.25 mcg to 0.5 mcg
2
0.5 mcg to 1 mcg
1
1 mcg to 2.5 mcg
1
2.5 mcg to 5 mcg
10
over 5 mcg
1

Commonly used together

16 of 16 study groups took Iron, Selenium, Vitamin A, Copper and Vitamin B12 with something else. Shown: what 3 or more different studies gave. The 10 most common of 12.

What was given together, not what works together.

Taken withStudy groups
Iodine
16
Vitamin C
16
Vitamin E
16
Zinc
16
Folic Acid
15
Vitamin B6
15
Vitamin D
15
Niacin
12
vitamin B2
7
vitamin B1
6

16 study groups

Study
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · EMMS (early food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg65 mcg800 mcg2 mg2.6 mcg——
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · UMMS (usual food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg65 mcg800 mcg2 mg2.6 mcg——
Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren
2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified
18 mg40 mcg1 mg2 mg2 mcg335 days—
Predictors of adherence to micronutrient supplementation before and during pregnancy in Vietnam
2017 · MM (multiple micronutrients) preconception group · Women of reproductive age in Vietnam intending to become pregnant
8.57 mg9.29 mcg114 mcg286 mcg0.371 mcg54 weeks1,469
Effects of antenatal multiple micronutrient supplementation on children's weight and size at 2 years of age in Nepal: follow-up of a double-blind randomised controlled trial
2008 · intervention group · Pregnant women enrolled at no earlier than 12 weeks’ gestation, with singleton pregnancies and gestation up to 20 completed weeks
30 mg65 mcg800 mcg2 mg2.6 mcg—600
Effect of antenatal multiple micronutrient supplementation on anthropometry and blood pressure in mid-childhood in Nepal: follow-up of a double-blind randomised controlled trial
2014 · intervention group (multiple micronutrient supplement) · Pregnant women attending antenatal care in Nepal; no specific age range or deficiency criterion stated
30 mg65 mcg800 mcg2 mg2.6 mcg—600
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-180 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg65 mcg800 mcg2 mg2.6 mcg180 days516
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-90 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg65 mcg800 mcg2 mg2.6 mcg180 days515
Associations of antenatal micronutrient supplementation with adolescent blood pressure: evidence from a 14-year follow-up study of a randomized controlled trial
2025 · Multiple micronutrients (MMNs; UNIMMAP formulation) · Pregnant women less than 28 weeks of gestation; offspring were followed up at ages 10–14 years
30 mg——2 mg———
Impact of Preconception Micronutrient Supplementation on Anemia and Iron Status during Pregnancy and Postpartum: A Randomized Controlled Trial in Rural Vietnam
2016 · Multiple micronutrients (MM) · Women aged 18–40 planning pregnancy in rural Vietnam; no specific diagnosed condition required
8.57 mg9.29 mcg114 mcg286 mcg0.371 mcg56 weeks508
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
27 mg60 mcg770 mcg1 mg2.6 mcg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
27 mg60 mcg770 mcg1 mg2.6 mcg—176
Effects of prenatal micronutrient and early food supplementation on metabolic status of the offspring at 4.5 years of age. The MINIMat randomized trial in rural Bangladesh
2016 · MMS · Pregnant women in rural Bangladesh; offspring assessed at 4.5 years
30 mg65 mcg—2 mg2.6 mcg—439
Maternal cortisol and stress are associated with birth outcomes, but are not affected by lipid-based nutrient supplements during pregnancy: an analysis of data from a randomized controlled trial in rural Malawi
2015 · MMN · Pregnant women aged 15–49 years in rural Malawi, enrolled at up to 20 weeks of gestation
20 mg130 mcg800 mcg4 mg5.2 mcg—415
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
10 mg17 mcg400 mcg560 mcg0.9 mcg22 weeks175
Host iron status and erythropoietic response to iron supplementation determines susceptibility to the RBC stage of falciparum malaria during pregnancy
2017 · Reference (standard-of-care) arm · Pregnant women aged 18–45 years, recruited at 14–22 weeks’ gestation in rural Gambia; healthy at enrolment, with varying anaemia and iron status
60 mg65 mcg800 mcg2 mg2.6 mcg12 weeks—
Iron, Selenium, Vitamin A, Copper and Vitamin B12: study protocols | supp.fit