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All Iron study protocols

Iron, Iodine, Vitamin B12 and Vitamin D: study protocols

11 study groups took Iron together with Iodine, Vitamin B12 and Vitamin D. These are the doses the studies gave. They are not a recommendation.

Iron: what the research found →

Dose per serving from research: Iron

11 study groups in 9 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 64% of 11 study groups.

Daily doseStudy groups
5 mg to 10 mg
3
10 mg to 25 mg
1
25 mg to 50 mg
7

Dose per serving from research: Iodine

10 study groups in 8 studies say how much Iodine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mcg to 250 mcg, 70% of 10 study groups.

Daily doseStudy groups
25 mcg or less
1
25 mcg to 50 mcg
2
50 mcg to 100 mcg
0
100 mcg to 250 mcg
7

Dose per serving from research: Vitamin B12

10 study groups in 8 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 60% of 10 study groups.

Daily doseStudy groups
0.5 mcg or less
1
0.5 mcg to 1 mcg
2
1 mcg to 2.5 mcg
0
2.5 mcg to 5 mcg
6
over 5 mcg
1

Dose per serving from research: Vitamin D

5 study groups in 5 studies say how much Vitamin D participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 80% of 5 study groups.

Daily doseStudy groups
2.5 mcg to 5 mcg
4
5 mcg to 10 mcg
1

Commonly used together

11 of 11 study groups took Iron, Iodine, Vitamin B12 and Vitamin D with something else. Shown: what 3 or more different studies gave. The 10 most common of 12.

What was given together, not what works together.

Taken withStudy groups
Zinc
11
Copper
10
Vitamin A
10
Vitamin B6
10
Vitamin C
10
Vitamin E
10
Folic Acid
9
Niacin
8
Selenium
8
Riboflavin
4

11 study groups

Study
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · EMMS (early food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg150 mcg2.6 mcg200 IU——
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · UMMS (usual food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg150 mcg2.6 mcg200 IU——
Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa
2009 · multiple micronutrients · children aged 6–24 months; three cohorts: HIV-infected children, HIV-uninfected children born to HIV-infected mothers, and HIV-uninfected children born to HIV-uninfected mothers
10 mg50 mcg0.9 mcg5 mcg548 days—
Predictors of adherence to micronutrient supplementation before and during pregnancy in Vietnam
2017 · MM (multiple micronutrients) preconception group · Women of reproductive age in Vietnam intending to become pregnant
8.57 mg21.4 mcg0.371 mcg85.7 IU54 weeks1,469
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-180 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg150 mcg2.6 mcg200 IU180 days516
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-90 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg150 mcg2.6 mcg200 IU180 days515
Effect on longitudinal growth and anemia of zinc or multiple micronutrients added to vitamin A: a randomized controlled trial in children aged 6-24 months
2010 · Multiple micronutrients · Children enrolled at 6 months and followed to 24 months in rural South Africa; HIV-infected and HIV-uninfected children, both sexes
10 mg50 mcg0.9 mcg5 mcg548 days126
Associations of antenatal micronutrient supplementation with adolescent blood pressure: evidence from a 14-year follow-up study of a randomized controlled trial
2025 · Multiple micronutrients (MMNs; UNIMMAP formulation) · Pregnant women less than 28 weeks of gestation; offspring were followed up at ages 10–14 years
30 mg—————
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
12 mg150 mcg5.2 mcg10 mcg—870
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
27 mg220 mcg2.6 mcg5 mcg165 days749