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All Iron study protocols

Iron, Folic Acid, Zinc and Vitamin C: study protocols

16 study groups took Iron together with Folic Acid, Zinc and Vitamin C. These are the doses the studies gave. They are not a recommendation.

Iron: what the research found →

Dose per serving from research: Iron

16 study groups in 12 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 56% of 16 study groups.

Daily doseStudy groups
5 mg or less
1
5 mg to 10 mg
2
10 mg to 25 mg
2
25 mg to 50 mg
9
50 mg to 100 mg
2

Dose per serving from research: Folic Acid

15 study groups in 11 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 53% of 15 study groups.

Daily doseStudy groups
100 mcg to 250 mcg
5
250 mcg to 500 mcg
8
500 mcg to 1 mg
2

Dose per serving from research: Zinc

16 study groups in 12 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 50% of 16 study groups.

Daily doseStudy groups
2.5 mg or less
1
2.5 mg to 5 mg
4
5 mg to 10 mg
1
10 mg to 25 mg
8
25 mg to 50 mg
2

Dose per serving from research: Vitamin C

16 study groups in 12 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg to 100 mg, 50% of 16 study groups.

Daily doseStudy groups
10 mg or less
1
10 mg to 25 mg
0
25 mg to 50 mg
5
50 mg to 100 mg
8
100 mg to 250 mg
2

Commonly used together

16 of 16 study groups took Iron, Folic Acid, Zinc and Vitamin C with something else. Shown: what 3 or more different studies gave. The 10 most common of 11.

What was given together, not what works together.

Taken withStudy groups
Vitamin A
16
Copper
12
Iodine
12
Selenium
12
Vitamin E
12
Vitamin D
11
Niacin
9
Vitamin B12
9
Vitamin B6
8
Riboflavin
5

16 study groups

Study
Impact of micronutrient supplementation during pregnancy on birth weight, duration of gestation, and perinatal mortality in rural western China: double blind cluster randomised controlled trial
2008 · Multiple micronutrients · Pregnant women resident in disadvantaged rural counties in Shaanxi Province, China; eligible women enrolled before 28 weeks’ gestation
30 mg400 mcg15 mg70 mg—1,899
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · EMMS (early food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg400 mcg15 mg70 mg——
Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh
2014 · UMMS (usual food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation
30 mg400 mcg15 mg70 mg——
Predictors of adherence to micronutrient supplementation before and during pregnancy in Vietnam
2017 · MM (multiple micronutrients) preconception group · Women of reproductive age in Vietnam intending to become pregnant
8.57 mg400 mcg2.14 mg10 mg54 weeks1,469
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-180 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg400 mcg15 mg70 mg180 days516
Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia
2025 · MMS-90 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy
30 mg400 mcg15 mg70 mg180 days515
Associations of antenatal micronutrient supplementation with adolescent blood pressure: evidence from a 14-year follow-up study of a randomized controlled trial
2025 · Multiple micronutrients (MMNs; UNIMMAP formulation) · Pregnant women less than 28 weeks of gestation; offspring were followed up at ages 10–14 years
30 mg—15 mg70 mg——
Effect of Micronutrient Powder (MNP) with a Low-Dose of Iron on Hemoglobin and Iron Biomarkers, and Its Effect on Morbidities in Rural Bangladeshi Children Drinking Groundwater with a High-Level of Iron: A Randomized Controlled Trial
2019 · low-dose-iron MNP · Bangladeshi children aged 2–5 years drinking groundwater with a high level of iron
5 mg150 mcg5 mg30 mg60 days—
Effect of Micronutrient Powder (MNP) with a Low-Dose of Iron on Hemoglobin and Iron Biomarkers, and Its Effect on Morbidities in Rural Bangladeshi Children Drinking Groundwater with a High-Level of Iron: A Randomized Controlled Trial
2019 · standard MNP · Bangladeshi children aged 2–5 years drinking groundwater with a high level of iron
12.5 mg150 mcg5 mg30 mg60 days—
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
27 mg600 mcg12 mg85 mg165 days749