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Inositol and Folic Acid: study protocols

11 study groups took Inositol together with Folic Acid. These are the doses the studies gave. They are not a recommendation.

Inositol: what the research found →

Dose per serving from research: Inositol

11 study groups in 10 studies say how much Inositol participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 g to 5 g, 100% of 11 study groups.

Daily doseStudy groups
2.5 g to 5 g
11

Dose per serving from research: Folic Acid

10 study groups in 9 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 100% of 10 study groups.

Daily doseStudy groups
250 mcg to 500 mcg
10

Commonly used together

5 of 11 study groups took Inositol and Folic Acid with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Calcium
4
Iodine
4
Iron
4
Probiotics
4
Riboflavin
4
Vitamin B12
4
Vitamin B6
4
Vitamin D
4
Zinc
4
β-carotene
3

11 study groups

Study
Myo-inositol Supplementation for Prevention of Gestational Diabetes in Obese Pregnant Women: A Randomized Controlled Trial
2015 · myo-inositol · Pregnant obese women (prepregnancy BMI 30 or greater)
4 g400 mcg—110
Myo-inositol may prevent gestational diabetes onset in overweight women: a randomized, controlled trial
2016 · myo-inositol group · Pregnant overweight, non-obese women with pre-pregnancy BMI ≥25 and <30 kg/m²
4 g400 mcg—110
Effect of dietary myo-inositol supplementation on the insulin resistance and the prevention of gestational diabetes mellitus: an open-label, randomized controlled trial
2024 · MI group · Pregnant women at 11–13+6 weeks of gestation
4 g400 mcg—100
myo-Inositol supplementation and onset of gestational diabetes mellitus in pregnant women with a family history of type 2 diabetes: a prospective, randomized, placebo-controlled study
2013 · myo-inositol group · Pregnant women recruited at 12–13 weeks’ gestation with a first-degree relative with type 2 diabetes, prepregnancy BMI <30 kg/m², and no pregestational diabetes or PCOS
4 g400 mcg——
Higher Plasma Myo-Inositol in Pregnancy Associated with Reduced Postpartum Blood Loss: Secondary Analyses of the NiPPeR Trial
2024 · intervention supplement · Women aged 18–38 years planning conception; those included in this analysis conceived and had a singleton live birth
4 g——293
Myoinositol/folic acid combination for the treatment of erectile dysfunction in type 2 diabetes men: a double-blind, randomized, placebo-controlled study
2006 · myoinositol/folic acid combination · men with type 2 diabetes and erectile dysfunction
4 g400 mcg——
Impact of preconception and antenatal supplementation with myo-inositol, probiotics, and micronutrients on offspring BMI and weight gain over the first 2 years
2024 · Intervention group · Offspring of women aged 18–38 years recruited while planning pregnancy; mothers received the supplement before conception and during pregnancy
4 g400 mcg—287
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
4 g400 mcg—870
Effect of myo-inositol and melatonin versus myo-inositol, in a randomized controlled trial, for improving in vitro fertilization of patients with polycystic ovarian syndrome
2016 · Group A · Women of reproductive age with polycystic ovarian syndrome undergoing IVF
4 g400 mcg——
Effect of myo-inositol and melatonin versus myo-inositol, in a randomized controlled trial, for improving in vitro fertilization of patients with polycystic ovarian syndrome
2016 · Group B · Women of reproductive age with polycystic ovarian syndrome undergoing IVF
4 g400 mcg——