supp.fit

DIM: study protocols

11 study groups say how much DIM participants took a day. These are the doses the studies gave. They are not a recommendation.

DIM: what the research found →

Dose per serving from products

445 products in our catalogue print how much DIM a serving holds.

Most common: 50 mg to 100 mg, 34% of 445 products.

Dose per servingProducts
10 mg or less
12
10 mg to 25 mg
23
25 mg to 50 mg
54
50 mg to 100 mg
151
100 mg to 250 mg
133
250 mg to 500 mg
68
over 500 mg
4

Dose per serving from research

11 study groups in 5 studies say how much DIM participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg and 250 mg to 500 mg, 36% of 11 study groups each.

Daily doseStudy groups
50 mg or less
1
50 mg to 100 mg
2
100 mg to 250 mg
4
250 mg to 500 mg
4

Commonly used together

None of these 11 study groups took DIM with anything else.

11 study groups

Study
Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjects
2008 · 100 mg DIM group · Healthy men and women aged 22–58 years
100 mg1 day3
Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjects
2008 · 150 mg DIM group · Healthy men and women aged 22–58 years
150 mg1 day3
Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer
2004 · DIM treatment group · Postmenopausal women aged 50–70 with a history of early-stage breast cancer
108 mg30 days10
Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjects
2008 · 50 mg DIM group · Healthy men and women aged 22–58 years
50 mg1 day3
Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjects
2008 · 200 mg DIM group · Healthy men and women aged 22–58 years
200 mg1 day3
Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjects
2008 · 300 mg DIM group, first group · Healthy men and women aged 22–58 years
300 mg1 day3
Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjects
2008 · 300 mg DIM group, second group · Healthy men and women aged 22–58 years
300 mg1 day3
Phase Ib placebo-controlled, tissue biomarker trial of diindolylmethane (BR-DIMNG) in patients with prostate cancer who are undergoing prostatectomy
2016 · 100 mg BR-DIM group · Adults with organ-confined prostate cancer scheduled for radical prostatectomy; age and sex are not specified in the abstract.
200 mg4 weeks—
A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen
2017 · DIM · Women over 18 taking tamoxifen for at least 3 months for primary prevention or adjuvant therapy for early-stage breast cancer
300 mg548 days65
Effectiveness of 3,3'-Diindolylmethane Supplements on Favoring the Benign Estrogen Metabolism Pathway and Decreasing Body Fat in Premenopausal Women
2023 · DIM group · Premenopausal Mexican women with an EMUR below 0.9
75 mg30 days—
Phase Ib placebo-controlled, tissue biomarker trial of diindolylmethane (BR-DIMNG) in patients with prostate cancer who are undergoing prostatectomy
2016 · 200 mg BR-DIM group · Adults with organ-confined prostate cancer scheduled for radical prostatectomy; age and sex are not specified in the abstract.
400 mg4 weeks—