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Creatine and Folic Acid: study protocols

6 study groups took Creatine together with Folic Acid. These are the doses the studies gave. They are not a recommendation.

Creatine: what the research found →

Dose per serving from research: Creatine

6 study groups in 6 studies say how much Creatine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 g to 5 g, 100% of 6 study groups.

Daily doseStudy groups
2.5 g to 5 g
6

Dose per serving from research: Folic Acid

6 study groups in 6 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 100% of 6 study groups.

Daily doseStudy groups
250 mcg to 500 mcg
6

Commonly used together

None of these 6 study groups took Creatine and Folic Acid with anything else.

6 study groups

Study
Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults
2021 · creatine+400FA · Adults aged 24–55 in Bangladesh exposed to arsenic through household drinking water
3 g400 mcg12 weeks104
Folic Acid and Creatine as Therapeutic Approaches to Lower Blood Arsenic: A Randomized Controlled Trial
2015 · Creatine plus FA400, first phase · Adults aged 20–65 in Bangladesh selected for drinking from a well with arsenic above 50 μg/L; both folate-deficient and folate-sufficient participants
3 g400 mcg12 weeks103
Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial
2015 · Cr+FA group · Bangladeshi adults
3 g400 mcg12 weeks103
The Folic Acid and Creatine Trial: Treatment Effects of Supplementation on Arsenic Methylation Indices and Metabolite Concentrations in Blood in a Bangladeshi Population
2023 · creatine + 400FA · Adults aged 20–65 years in Bangladesh exposed to arsenic in drinking water; men and women, recruited independent of folate status
3 g400 mcg12 weeks103
Supplementation with Folic Acid, but Not Creatine, Increases Plasma Betaine, Decreases Plasma Dimethylglycine, and Prevents a Decrease in Plasma Choline in Arsenic-Exposed Bangladeshi Adults
2016 · Creatine plus FA400 · Arsenic-exposed adults aged 24–55 in Bangladesh
3 g400 mcg12 weeks—
Folic acid supplementation enhances arsenic methylation: results from a folic acid and creatine supplementation randomized controlled trial in Bangladesh
2019 · 400 μg folic acid plus 3 g creatine group · Bangladeshi participants exposed to arsenic through drinking water; the majority were folate sufficient
3 g400 mcg24 weeks—