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Chitosan: study protocols

21 study groups say how much Chitosan participants took a day. These are the doses the studies gave. They are not a recommendation.

Chitosan: what the research found →

Dose per serving from products

42 products in our catalogue print how much Chitosan a serving holds.

Most common: 500 mg to 1 g, 40% of 42 products.

Dose per servingProducts
100 mg or less
1
100 mg to 250 mg
11
250 mg to 500 mg
5
500 mg to 1 g
17
1 g to 2.5 g
7
over 2.5 g
1

Dose per serving from research

21 study groups in 15 studies say how much Chitosan participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 g to 2.5 g, 48% of 21 study groups.

Daily doseStudy groups
250 mg or less
1
250 mg to 500 mg
2
500 mg to 1 g
1
1 g to 2.5 g
10
2.5 g to 5 g
7

Commonly used together

3 of 21 study groups took Chitosan with something else, but nothing that 3 or more different studies gave.

21 study groups

Study
Single-blind, placebo controlled randomised clinical study of chitosan for body weight reduction
2016 · chitosan group · Adults aged 18–65, both sexes, with BMI 26–35 and excess weight
1.5 g90 days64
The effects of chitosan supplementation on anthropometric indicators of obesity, lipid and glycemic profiles, and appetite-regulated hormones in adolescents with overweight or obesity: a randomized, double-blind clinical trial
2022 · Chitosan · Adolescent girls and boys aged 10–19 years with overweight or obesity
3 g12 weeks31
L-ascorbic acid addition to chitosan reduces body weight in overweight women
2014 · Chito group · Overweight women
3 g8 weeks27
Chitosan improves insulin sensitivity as determined by the euglycemic-hyperinsulinemic clamp technique in obese subjects
2010 · chitosan · Obese adults without diabetes mellitus
2.25 g90 days6
[Effect of chitosan in complex management of obesity]
2002 · chitosan group · Women aged 22–59 with obesity (BMI >30)
2.25 g26 weeks—
Evaluating efficacy of a chitosan product using a double-blinded, placebo-controlled protocol
2006 · treatment group (TRT) · Overweight adults; age range and sex distribution for this arm not stated
3 g——
L-ascorbic acid addition to chitosan reduces body weight in overweight women
2014 · Chito-vita group · Overweight women
3 g8 weeks27
Regular Consumption of Lipigo(®) Promotes the Reduction of Body Weight and Improves the Rebound Effect of Obese People Undergo a Comprehensive Weight Loss Program
2020 · Lipigo® group · Men and women aged 18–65 years with BMI ≥27 and <40 kg/m², participating in a weight-control program
273 mg52 weeks—
Influence of Chitosan Treatment on Surrogate Serum Markers of Cholesterol Metabolism in Obese Subjects
2018 · chitosan group · Adults aged 18–65 years with BMI 28–36 kg/m² and elevated waist circumference, described as highly overweight or obese; no relevant diseases
3 g12 weeks61
Efficacy and safety of chitosan HEP-40 in the management of hypercholesterolemia: a randomized, multicenter, placebo-controlled trial
2007 · HEP-40 400 mg three times daily · Adults with low-to-moderate hypercholesterolemia, treatment-naive for lipid-lowering medications
1.2 g12 weeks—
Efficacy and safety of chitosan HEP-40 in the management of hypercholesterolemia: a randomized, multicenter, placebo-controlled trial
2007 · HEP-40 800 mg twice daily · Adults with low-to-moderate hypercholesterolemia, treatment-naive for lipid-lowering medications
1.6 g12 weeks—
Efficacy and safety of chitosan HEP-40 in the management of hypercholesterolemia: a randomized, multicenter, placebo-controlled trial
2007 · HEP-40 800 mg three times daily · Adults with low-to-moderate hypercholesterolemia, treatment-naive for lipid-lowering medications
2.4 g12 weeks—
Efficacy and safety of chitosan HEP-40 in the management of hypercholesterolemia: a randomized, multicenter, placebo-controlled trial
2007 · HEP-40 2,400 mg once daily · Adults with low-to-moderate hypercholesterolemia, treatment-naive for lipid-lowering medications
2.4 g12 weeks—
Effect of chitosan on lipid levels when administered concurrently with atorvastatin--a placebo controlled study
2005 · Group A · Patients with chronic coronary heart disease; age and sex not reported
2 g6 weeks50
Chitosan decreases total cholesterol in women: a randomized, double-blind, placebo-controlled trial
2003 · chitosan · Women aged 34–70 with confirmed mild to moderate hypercholesterolemia
1.2 g8 weeks41
The effect of chitosan supplementation on liver function, hepatic steatosis predictors, and metabolic indicators in adults with non-alcoholic fatty liver disease: a randomized, double-blinded, placebo-controlled, clinical trial
2025 · Chitosan · Adults aged 18–65 with non-alcoholic fatty liver disease (grades 1–3)
1.5 g8 weeks36
The effects of chitosan supplementation on anthropometric indicators of obesity, lipid and glycemic profiles, and appetite-regulated hormones in adolescents with overweight or obesity: a randomized, double-blind clinical trial
2022 · Chitosan · Adolescent girls and boys aged 10–19 years with overweight or obesity
3 g12 weeks31
The Effect of Chitosan Supplementation on the Gut Microbiota and Various Health Factors in Icelandic Females: A Placebo-Controlled, Double-Blind, Randomized Trial
2025 · TRG (chitosan group) · Icelandic females aged 26–70 with BMI 19.1–35.0 kg/m²
3 g12 weeks28
The Influence of Chitosan on the Oral Bioavailability of Acyclovir--a Comparative Bioavailability Study in Humans
2015 · Zovirax + 400 mg chitosan HCl · Healthy adult male and female volunteers; age range not reported
400 mg1 day12
The Influence of Chitosan on the Oral Bioavailability of Acyclovir--a Comparative Bioavailability Study in Humans
2015 · Zovirax + 1000 mg chitosan HCl · Healthy adult male and female volunteers; age range not reported
1 g1 day12
Effects of a New Nutraceutical Formulation (Berberine, Red Yeast Rice and Chitosan) on Non-HDL Cholesterol Levels in Individuals with Dyslipidemia: Results from a Randomized, Double Blind, Placebo-Controlled Study
2017 · Nutraceutical compound · Men and women aged 18–75 with hypercholesterolemia and non-HDL-C ≥160 mg/dL
10 mg12 weeks30
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