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Caffeine, Vitamin B12 and Niacin: study protocols

8 study groups took Caffeine together with Vitamin B12 and Niacin. These are the doses the studies gave. They are not a recommendation.

Caffeine: what the research found →

Dose per serving from research: Caffeine

8 study groups in 5 studies say how much Caffeine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg and 250 mg to 500 mg, 50% of 8 study groups each.

Daily doseStudy groups
100 mg to 250 mg
4
250 mg to 500 mg
4

Dose per serving from research: Vitamin B12

7 study groups in 4 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg to 100 mg, 57% of 7 study groups.

Daily doseStudy groups
5 mcg to 10 mcg
1
10 mcg to 25 mcg
1
25 mcg to 50 mcg
1
50 mcg to 100 mcg
0
100 mcg to 250 mcg
0
250 mcg to 500 mcg
0
500 mcg to 1 mg
0
1 mg to 2.5 mg
0
2.5 mg to 5 mg
0
5 mg to 10 mg
0
10 mg to 25 mg
0
25 mg to 50 mg
0
50 mg to 100 mg
4

Dose per serving from research: Niacin

8 study groups in 5 studies say how much Niacin participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg to 100 mg, 63% of 8 study groups.

Daily doseStudy groups
25 mg to 50 mg
3
50 mg to 100 mg
5

Commonly used together

8 of 8 study groups took Caffeine, Vitamin B12 and Niacin with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Beta-Alanine
6
Folic Acid
5

8 study groups

Study
Acute effects of commercial energy drink consumption on exercise performance and cardiovascular safety: a randomized, double-blind, placebo-controlled, crossover trial
2024 · C4E (C4 Energy drink) · Healthy, physically active men aged 20–35 years
200 mg6 mcg30 mg1 day30
Acute effects of commercial energy drink consumption on exercise performance and cardiovascular safety: a randomized, double-blind, placebo-controlled, crossover trial
2024 · MED (Monster Energy caffeine drink) · Healthy, physically active men aged 20–35 years
160 mg12 mcg30 mg1 day30
Effects of ingesting a pre-workout dietary supplement with and without synephrine for 8 weeks on training adaptations in resistance-trained males
2017 · PWS · Apparently healthy, resistance-trained males; mean age about 21 years
284 mg70 mg60 mg8 weeks27
Effects of ingesting a pre-workout dietary supplement with and without synephrine for 8 weeks on training adaptations in resistance-trained males
2017 · PWS + S · Apparently healthy, resistance-trained males; mean age about 22 years
284 mg70 mg60 mg8 weeks26
Effects of acute ingestion of a pre-workout dietary supplement with and without p-synephrine on resting energy expenditure, cognitive function and exercise performance
2017 · PWS · Resistance-trained healthy adults; 20 men and 5 women, mean age 21.7 years
284 mg70 mg60 mg1 day25
Effects of acute ingestion of a pre-workout dietary supplement with and without p-synephrine on resting energy expenditure, cognitive function and exercise performance
2017 · PWS + S · Resistance-trained healthy adults; 20 men and 5 women, mean age 21.7 years
284 mg70 mg60 mg1 day25
Short-Term Effects of a Ready-to-Drink Pre-Workout Beverage on Exercise Performance and Recovery
2017 · RTD · Recreationally active men and women aged 18–40 years with at least six months of resistance-training experience
200 mg45 mcg65 mg7 days25
Improved cycling time-trial performance after ingestion of a caffeine energy drink
2009 · Red Bull Energy Drink · Trained male and female cyclists; mean age 27.3 years
160 mg—40 mg1 day12
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