supp.fit

Bromelain: study protocols

15 study groups say how much Bromelain participants took a day. These are the doses the studies gave. They are not a recommendation.

Bromelain: what the research found →

Dose per serving from products

2,382 products in our catalogue print how much Bromelain a serving holds.

Most common: 10 mg to 25 mg, 29% of 2,382 products.

Dose per servingProducts
5 mg or less
118
5 mg to 10 mg
127
10 mg to 25 mg
691
25 mg to 50 mg
326
50 mg to 100 mg
356
100 mg to 250 mg
400
250 mg to 500 mg
265
over 500 mg
99

Dose per serving from research

15 study groups in 12 studies say how much Bromelain participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg, 47% of 15 study groups.

Daily doseStudy groups
100 mg or less
1
100 mg to 250 mg
7
250 mg to 500 mg
4
500 mg to 1 g
2
1 g to 2.5 g
0
over 2.5 g
1

Commonly used together

7 of 15 study groups took Bromelain with something else, but nothing that 3 or more different studies gave.

15 study groups

Study
Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis
2016 · bromelain · Adults with mild-to-moderate knee osteoarthritis
500 mg16 weeks—
Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study
2025 · intervention group (bromelain group) · Adults aged 18–70 with active mild-to-moderate ulcerative colitis
400 mg8 weeks35
The effect of bromelain in periodontal surgery: a double-blind randomized placebo-controlled trial
2023 · Anaheal · Adults aged 18–70 with chronic periodontitis who had completed phase I periodontal therapy and had pocket probing depth ≥5 mm, undergoing pocket elimination surgery
1 g7 days14
Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults
2002 · high-dose group · Otherwise healthy adults with mild acute knee pain lasting less than 3 months
400 mg30 days—
Perioperative bromelain reduces pain and swelling and improves quality of life measures after mandibular third molar surgery: a randomized, double-blind, placebo-controlled clinical trial
2014 · bromelain group · Patients requiring extraction of a single partially bony impacted mandibular third molar; age and sex not specified
1 g5 days—
Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery
2025 · Group B: CBB + placebo · Women aged over 18 with breast cancer undergoing breast-conserving surgery
200 mg30 days37
Analgesic Efficacy of Bromelain and Bromelain Plus Turmeric for Pain Control After Orthodontic Separator Placement: A Triple-Blind Randomized Clinical Trial
2025 · Group B (ANAHEAL) · Patients older than 15 years receiving orthodontic separators; both sexes
200 mg1 day40
Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults
2002 · low-dose group · Otherwise healthy adults with mild acute knee pain lasting less than 3 months
200 mg30 days—
Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery
2025 · Group A: CBB + neurotrophic agents · Women aged over 18 with breast cancer undergoing breast-conserving surgery
200 mg30 days39
Systemic enzyme therapy for postoperative inflammation and wound healing after orthopedic surgery: a randomized, placebo and active controlled clinical study
2025 · Group B (comparator product) · Adults aged 25–50 undergoing elective orthopedic surgery
180 mg7 days42
Analgesic Efficacy of Bromelain and Bromelain Plus Turmeric for Pain Control After Orthodontic Separator Placement: A Triple-Blind Randomized Clinical Trial
2025 · Group C (ANAHEAL PLUS) · Patients older than 15 years receiving orthodontic separators; both sexes
150 mg1 day41
Bromelain-Rich Pineapple Extract for the Treatment of Pediatric Patients With Orchiepididymitis: A Randomized Clinical Pilot Study
2025 · Brome-Inf · Males aged 6–18 years with orchiepididymitis and preserved renal function
5.5 g15 days30
A Nutraceutical Combination of Bromelain and Boswellia Serrata Casperome® in Siben®: Effects on the Postoperative Course of Inguinal Hernioplasty with Mesh at One Year Follow up. A Randomized Multicentric Study
2024 · study group · Adults undergoing open inguinal hernioplasty with mesh; age and sex details for this arm not reported
400 mg11 days—
Efficacy and safety of Atusin(®) CAP in the treatment of acute uncomplicated bronchitis in the primary care setting: a multi-center, randomized, double-blind, placebo-controlled study (AABA)
2025 · verum group · Adults with acute uncomplicated bronchitis; mean age 39.5 years, 66.5% female
240 mg10 days155
Effects of Macuprev(®) Supplementation in Age-Related Macular Degeneration: A Double-Blind Randomized Morpho-Functional Study Along 6 Months of Follow-Up
2019 · AMD-M group · Adults with intermediate age-related macular degeneration; 9 male and 21 female enrolled overall, mean age 69.32 years
80 mg26 weeks15