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Phytosterols and Omega-3 Fatty Acids: study protocols

13 study groups took Phytosterols together with Omega-3 Fatty Acids. These are the doses the studies gave. They are not a recommendation.

Phytosterols: what the research found →

Dose per serving from research: Phytosterols

12 study groups in 8 studies say how much Phytosterols participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 g to 2.5 g, 92% of 12 study groups.

Daily doseStudy groups
1 g to 2.5 g
11
2.5 g to 5 g
1

Dose per serving from research: Omega-3 Fatty Acids

12 study groups in 8 studies say how much Omega-3 Fatty Acids participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 g to 2.5 g, 83% of 12 study groups.

Daily doseStudy groups
500 mg to 1 g
2
1 g to 2.5 g
10

Commonly used together

4 of 13 study groups took Phytosterols and Omega-3 Fatty Acids with something else, but nothing that 3 or more different studies gave.

13 study groups

Study
Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects
2007 · PS-FO · Men and postmenopausal women aged 30–65 years with mildly overweight hypercholesterolemia
1.7 g1.7 g4 weeks21
Reduction in Serum LDL Cholesterol Using a Nutrient Compendium in Hyperlipidemic Adults Unable or Unwilling to Use Statin Therapy: A Double-Blind Randomized Crossover Clinical Trial
2022 · Treatment foods · Adult men and women with hyperlipidemia who were unable or unwilling to use statin therapy
2 g2 g4 weeks—
Consumption of an oil composed of medium chain triacyglycerols, phytosterols, and N-3 fatty acids improves cardiovascular risk profile in overweight women
2003 · functional oil (FctO) diet · Overweight women; age range not reported
22 mg/kg—27 days17
The lipid-lowering effects of phytosterols and (n-3) polyunsaturated fatty acids are synergistic and complementary in hyperlipidemic men and women
2008 · Combination of phytosterols and (n-3) LCPUFA · Men and women with hyperlipidemia; age range not reported
2 g1.4 g3 weeks—
Anti-inflammatory and cardioprotective effects of n-3 polyunsaturated fatty acids and plant sterols in hyperlipidemic individuals
2009 · n-3 PUFA capsules with plant sterols · Hyperlipidemic participants; age and sex not specified
2 g1.4 g3 weeks—
Low doses of eicosapentaenoic acid and docosahexaenoic acid from fish oil dose-dependently decrease serum triglyceride concentrations in the presence of plant sterols in hypercholesterolemic men and women
2014 · Intervention spread with 0.9 g/d EPA+DHA · Hypercholesterolemic men and women aged 25–74 years
2.5 g900 mg4 weeks—
Low doses of eicosapentaenoic acid and docosahexaenoic acid from fish oil dose-dependently decrease serum triglyceride concentrations in the presence of plant sterols in hypercholesterolemic men and women
2014 · Intervention spread with 1.3 g/d EPA+DHA · Hypercholesterolemic men and women aged 25–74 years
2.5 g1.3 g4 weeks—
Low doses of eicosapentaenoic acid and docosahexaenoic acid from fish oil dose-dependently decrease serum triglyceride concentrations in the presence of plant sterols in hypercholesterolemic men and women
2014 · Intervention spread with 1.8 g/d EPA+DHA · Hypercholesterolemic men and women aged 25–74 years
2.5 g1.8 g4 weeks—
The effect of plant sterols and different low doses of omega-3 fatty acids from fish oil on lipoprotein subclasses
2015 · PS (2.5 g/day) and EPA+DHA (0.9 g/day) spread · Hypercholesterolemic subjects; age and sex not specified
2.5 g900 mg4 weeks—
The effect of plant sterols and different low doses of omega-3 fatty acids from fish oil on lipoprotein subclasses
2015 · PS (2.5 g/day) and EPA+DHA (1.3 g/day) spread · Hypercholesterolemic subjects; age and sex not specified
2.5 g1.3 g4 weeks—
The effect of plant sterols and different low doses of omega-3 fatty acids from fish oil on lipoprotein subclasses
2015 · PS (2.5 g/day) and EPA+DHA (1.8 g/day) spread · Hypercholesterolemic subjects; age and sex not specified
2.5 g1.8 g4 weeks—
Combined effect of n-3 fatty acids and phytosterol esters on alleviating hepatic steatosis in non-alcoholic fatty liver disease subjects: a double-blind placebo-controlled clinical trial
2020 · PS + FO combination group · People with non-alcoholic fatty liver disease (NAFLD); age and sex not reported
3.3 g1.95 g——
A combination of omega-3 and plant sterols regulate glucose and lipid metabolism in individuals with impaired glucose regulation: a randomized and controlled clinical trial
2019 · PS plus omega-3 fatty acids group · Adults aged 51–65 with impaired glucose regulation
1.7 g1.4 g12 weeks41
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