Phenylalanine and L-Tyrosine: study protocols
13 study groups took Phenylalanine together with L-Tyrosine. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Phenylalanine
9 study groups in 3 studies say how much Phenylalanine participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 mg/kg to 10 mg/kg, 89% of 9 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg/kg to 10 mg/kg | 8 |
| 10 mg/kg to 25 mg/kg | 0 |
| over 25 mg/kg | 1 |
Dose per serving from research: L-Tyrosine
8 study groups in 2 studies say how much L-Tyrosine participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 mg/kg to 10 mg/kg, 38% of 8 study groups.
| Daily dose | Study groups |
|---|---|
| 2.5 mg/kg to 5 mg/kg | 2 |
| 5 mg/kg to 10 mg/kg | 3 |
| 10 mg/kg to 25 mg/kg | 2 |
| 25 mg/kg to 50 mg/kg | 1 |
Commonly used together
5 of 13 study groups took Phenylalanine and L-Tyrosine with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Essential Amino Acids | 4 |
13 study groups
| Study | ||||
|---|---|---|---|---|
| Age moderates the effect of acute dopamine depletion on passive avoidance learning 2015 · balanced/control amino acid beverage · Healthy adults aged 22–40 years, women and men, without a current psychiatric or neurological diagnosis | 4.3 g | 5.2 g | 1 day | 16 |
| Reliance on habits at the expense of goal-directed control following dopamine precursor depletion 2012 · BAL drink · Healthy men and women aged 19–49 without the listed psychiatric, neurological or major medical conditions | 12.5 g | 12.5 g | 1 day | 14 |
| Acute oral administration of a tyrosine and phenylalanine-free amino acid mixture reduces exercise capacity in the heat 2013 · BAL · Healthy, moderately trained men unacclimated to exercise in the heat | 12.5 g | 12.5 g | 1 day | 8 |
| The subjective and cognitive effects of acute phenylalanine and tyrosine depletion in patients recovered from depression 2005 · BAL balanced amino-acid mixture · Adults aged 24–55 years, men and women, recovered from at least one major depressive episode | 12.5 g | 12.5 g | 1 day | 17 |
| Protein to Maximize Whole-Body Anabolism in Resistance-trained Females after Exercise 2019 · randomized test protein intake · Resistance-trained females, mean age 23 years, studied during the luteal phase after whole-body resistance exercise | 30.5 mg/kg | 40 mg/kg | 1 day | 8 |
| In vivo regulation of phenylalanine hydroxylation to tyrosine, studied using enrichment in apoB-100 2008 · Seven graded tyrosine intake levels · Adult men; age and health condition not reported | 9 mg/kg | — | — | 6 |
| Effect of tyrosine intake on the rate of phenylalanine hydroxylation in adult males 2000 · 3.0 mg/kg/day tyrosine intake · healthy adult men | 9 mg/kg | 3 mg/kg | 1 day | — |
| Effect of tyrosine intake on the rate of phenylalanine hydroxylation in adult males 2000 · 4.5 mg/kg/day tyrosine intake · healthy adult men | 9 mg/kg | 4.5 mg/kg | 1 day | — |
| Effect of tyrosine intake on the rate of phenylalanine hydroxylation in adult males 2000 · 6.0 mg/kg/day tyrosine intake · healthy adult men | 9 mg/kg | 6 mg/kg | 1 day | — |
| Effect of tyrosine intake on the rate of phenylalanine hydroxylation in adult males 2000 · 7.5 mg/kg/day tyrosine intake · healthy adult men | 9 mg/kg | 7.5 mg/kg | 1 day | — |
| Effect of tyrosine intake on the rate of phenylalanine hydroxylation in adult males 2000 · 9.0 mg/kg/day tyrosine intake · healthy adult men | 9 mg/kg | 9 mg/kg | 1 day | — |
| Effect of tyrosine intake on the rate of phenylalanine hydroxylation in adult males 2000 · 10.5 mg/kg/day tyrosine intake · healthy adult men | 9 mg/kg | 10.5 mg/kg | 1 day | — |
| Effect of tyrosine intake on the rate of phenylalanine hydroxylation in adult males 2000 · 12.0 mg/kg/day tyrosine intake · healthy adult men | 9 mg/kg | 12 mg/kg | 1 day | — |