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Niacin and Riboflavin: study protocols

13 study groups took Niacin together with Riboflavin. These are the doses the studies gave. They are not a recommendation.

Niacin: what the research found →

Dose per serving from research: Niacin

13 study groups in 10 studies say how much Niacin participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 77% of 13 study groups.

Daily doseStudy groups
10 mg to 25 mg
2
25 mg to 50 mg
10
50 mg to 100 mg
1

Dose per serving from research: Riboflavin

13 study groups in 10 studies say how much Riboflavin participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg, 69% of 13 study groups.

Daily doseStudy groups
1 mg to 2.5 mg
2
2.5 mg to 5 mg
1
5 mg to 10 mg
9
10 mg to 25 mg
0
25 mg to 50 mg
1

Commonly used together

13 of 13 study groups took Niacin and Riboflavin with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Coenzyme Q10
7
Thiamine
4
Vitamin C
3
Vitamin E
3
Zinc
3

13 study groups

Study
Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren
2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified
16 mg1.6 mg335 days—
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
20 mg1.8 mg——
Efficacy and safety of the combined metabolic medication, containing inosine, nicotinamide, riboflavin and succinic acid, for the treatment of diabetic neuropathy: a multicenter randomized, double-blind, placebo-controlled parallel group clinical trial (CYLINDER)
2022 · Experimental group (SINR) · Men and women aged 45–74 with type 2 diabetes and symptomatic distal sensorimotor diabetic polyneuropathy
50 mg10 mg85 days108
Effects of vitamin-B complex supplementation on periodontal wound healing
2005 · Vit-B · Adults with generalized moderate to severe chronic periodontitis undergoing access flap surgery; ages not reported; 13 males and 17 females enrolled across the study
50 mg50 mg30 days—
Effect of coenzyme Q10, riboflavin and niacin on serum CEA and CA 15-3 levels in breast cancer patients undergoing tamoxifen therapy
2007 · Group IV (CoRN for 45 days) · Breast cancer patients undergoing tamoxifen therapy; age and sex not specified
50 mg10 mg45 days—
Effect of coenzyme Q10, riboflavin and niacin on serum CEA and CA 15-3 levels in breast cancer patients undergoing tamoxifen therapy
2007 · Group V (CoRN for 90 days) · Breast cancer patients undergoing tamoxifen therapy; age and sex not specified
50 mg10 mg90 days—
Serum cytokine levels of interleukin-1beta, -6, -8, tumour necrosis factor-alpha and vascular endothelial growth factor in breast cancer patients treated with tamoxifen and supplemented with co-enzyme Q(10), riboflavin and niacin
2007 · Group IV (CoRN for 45 days) · Breast cancer patients treated with tamoxifen
50 mg10 mg45 days—
Serum cytokine levels of interleukin-1beta, -6, -8, tumour necrosis factor-alpha and vascular endothelial growth factor in breast cancer patients treated with tamoxifen and supplemented with co-enzyme Q(10), riboflavin and niacin
2007 · Group V (CoRN for 90 days) · Breast cancer patients treated with tamoxifen
50 mg10 mg90 days—
Co-enzyme Q10, riboflavin and niacin supplementation on alteration of DNA repair enzyme and DNA methylation in breast cancer patients undergoing tamoxifen therapy
2008 · CoRN supplement plus tamoxifen · Breast cancer patients undergoing tamoxifen therapy
50 mg10 mg——
Anti-angiogenic potential of CoenzymeQ10, riboflavin and niacin in breast cancer patients undergoing tamoxifen therapy
2008 · Group IV (CoRN for 45 days) · Breast cancer patients receiving tamoxifen therapy for more than 1 year; age not reported
50 mg10 mg45 days—
Anti-angiogenic potential of CoenzymeQ10, riboflavin and niacin in breast cancer patients undergoing tamoxifen therapy
2008 · Group V (CoRN for 90 days) · Breast cancer patients receiving tamoxifen therapy for more than 1 year; age not reported
50 mg10 mg90 days—
Antioxidant micronutrients and biomarkers of oxidative stress and inflammation in colorectal adenoma patients: results from a randomized, controlled clinical trial
2010 · antioxidant micronutrient combination · Patients with a history of sporadic colorectal adenoma; age and sex not specified
80 mg7.2 mg120 days—
Effects of supplementation with low-dose group B vitamins on clinical and biochemical parameters in critically ill patients with COVID-19: a randomized clinical trial
2024 · intervention group · Critically ill patients with COVID-19
40 mg4 mg2 weeks40
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