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Glucosamine and Hyaluronic Acid: study protocols

7 study groups took Glucosamine together with Hyaluronic Acid. These are the doses the studies gave. They are not a recommendation.

Glucosamine: what the research found →

Dose per serving from research: Glucosamine

7 study groups in 7 studies say how much Glucosamine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 g to 2.5 g, 57% of 7 study groups.

Daily doseStudy groups
250 mg or less
1
250 mg to 500 mg
0
500 mg to 1 g
2
1 g to 2.5 g
4

Commonly used together

4 of 7 study groups took Glucosamine and Hyaluronic Acid with something else, but nothing that 3 or more different studies gave.

7 study groups

Study
Effects of ozone combined with articular injection of sodium hyaluronate on patients with knee osteoarthritis and their inflammatory factors and hemorheological indices
2023 · Control group · Adults aged 65–85 with knee osteoarthritis in one knee
1.5 g—5 weeks146
The effect of oral low molecular weight liquid hyaluronic acid combination with glucosamine and chondroitin on knee osteoarthritis patients with mild knee pain: An 8-week randomized double-blind placebo-controlled trial
2021 · A+HA group · Men and women aged 40 years or older with knee osteoarthritis and mild knee pain
750 mg50 mg8 weeks24
[Glucosamine hydrochloride combined with hyaluronate for temporomandibular joint osteoarthritis: a primary report of randomized controlled trial]
2011 · Intervention group · People with temporomandibular joint osteoarthritis
1.44 g—4 weeks14
Oral Glucosamine Hydrochloride Combined With Hyaluronate Sodium Intra-Articular Injection for Temporomandibular Joint Osteoarthritis: A Double-Blind Randomized Controlled Trial
2018 · group A · people with temporomandibular joint osteoarthritis
1.44 g—90 days—
A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial
2013 · Instaflex · Men and women aged 50–75 with self-reported joint pain lasting more than 3 months
1.5 g4 mg8 weeks49
A Dietary Supplement in the Management of Patients with Lumbar Osteochondrosis: A Randomized, Double-Blinded, Placebo-Controlled Study
2024 · supplement group · Adults with symptomatic MRI-confirmed lumbar osteochondrosis; age range and sex not specified
200 mg60 mg90 days26
Effects of 4-month treatment with glycocalyx dietary supplement on endothelial glycocalyx and vascular function after COVID-19 infection
2025 · GDS · Adults aged 18–75 with mild-to-moderate COVID-19 infection managed as outpatients
750 mg35 mg120 days29
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