Folic Acid and Iron: study protocols
146 study groups took Folic Acid together with Iron. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Folic Acid
146 study groups in 71 studies say how much Folic Acid participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mcg to 500 mcg, 76% of 146 study groups.
| Daily dose | Study groups |
|---|---|
| 50 mcg or less | 6 |
| 50 mcg to 100 mcg | 8 |
| 100 mcg to 250 mcg | 13 |
| 250 mcg to 500 mcg | 111 |
| 500 mcg to 1 mg | 5 |
| over 1 mg | 3 |
Dose per serving from research: Iron
137 study groups in 68 studies say how much Iron participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 50 mg to 100 mg, 43% of 137 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg to 10 mg | 17 |
| 10 mg to 25 mg | 15 |
| 25 mg to 50 mg | 43 |
| 50 mg to 100 mg | 59 |
| over 100 mg | 3 |
Commonly used together
71 of 146 study groups took Folic Acid and Iron with something else. Shown: what 3 or more different studies gave. The 10 most common of 14.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Zinc | 30 |
| Vitamin A | 28 |
| Vitamin B12 | 21 |
| Vitamin C | 19 |
| Iodine | 14 |
| Vitamin D | 14 |
| Vitamin E | 14 |
| Copper | 13 |
| Niacin | 12 |
| Selenium | 12 |
146 study groups
| Study | ||||
|---|---|---|---|---|
| Effects of prenatal micronutrients supplementation timing on pregnancy-induced hypertension: Secondary analysis of a double-blind randomized controlled trial 2021 · IFA group · Pregnant nulliparous Chinese women aged 20 or older, enrolled before 20 gestational weeks, with haemoglobin above 10.0 g/dl | 400 mcg | 30 mg | — | 6,252 |
| Micronutrient supplementation during pregnancy and the risk of pregnancy-induced hypertension: A randomized clinical trial 2019 · IFA group · Nulliparous pregnant women aged 20 years or older, enrolled before 20 weeks of gestation, with hemoglobin at least 10.0 g/dL | 400 mcg | 30 mg | — | 5,933 |
| Effects of Prenatal Micronutrient Supplementation on Spontaneous Preterm Birth: A Double-Blind Randomized Controlled Trial in China 2017 · IFA group · Pregnant women aged 20 years or older, nulliparous, enrolled before 20 gestational weeks, with hemoglobin above 10.0 g/dL | 400 mcg | 30 mg | — | 5,920 |
| Micronutrient supplementation during pregnancy and the risk of pregnancy-induced hypertension: A randomized clinical trial 2019 · MMN group · Nulliparous pregnant women aged 20 years or older, enrolled before 20 weeks of gestation, with hemoglobin at least 10.0 g/dL | 400 mcg | 30 mg | — | 5,914 |
| Effects of Prenatal Micronutrient Supplementation on Spontaneous Preterm Birth: A Double-Blind Randomized Controlled Trial in China 2017 · MMN group · Pregnant women aged 20 years or older, nulliparous, enrolled before 20 gestational weeks, with hemoglobin above 10.0 g/dL | 400 mcg | 30 mg | — | 5,910 |
| Excess risk of preterm birth with periconceptional iron supplementation in a malaria endemic area: analysis of secondary data on birth outcomes in a double blind randomized controlled safety trial in Burkina Faso 2019 · weekly iron and folic acid · Nulliparous, non-pregnant women aged 15–24 years in a malaria-endemic area of Burkina Faso who became pregnant during or shortly after supplementation | 400 mcg | 8.57 mg | 548 days | 980 |
| Cost-effectiveness of invitation to food supplementation early in pregnancy combined with multiple micronutrients on infant survival: analysis of data from MINIMat randomized trial, Bangladesh 2015 · EMMS · Pregnant women in rural Bangladesh, irrespective of nutritional status | 400 mcg | 30 mg | — | 740 |
| Nutrient supplementation during the first 1000 days and growth of infants born to pregnant adolescents 2020 · IFA-MNP · Pregnant adolescents under 20 years of age and their children | 400 mcg | 60 mg | — | 388 |
| Nutrient supplementation during the first 1000 days and growth of infants born to pregnant adolescents 2020 · IFA-Control · Pregnant adolescents under 20 years of age | 400 mcg | 60 mg | — | 378 |
| Nutrient supplementation during the first 1000 days and growth of infants born to pregnant adolescents 2020 · IFA-LNS · Pregnant adolescents under 20 years of age and their children | 400 mcg | 60 mg | — | 361 |