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Copper and Zinc: study protocols

10 study groups took Copper together with Zinc. These are the doses the studies gave. They are not a recommendation.

Copper: what the research found →

Dose per serving from research: Copper

10 study groups in 7 studies say how much Copper participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg and 1 mg to 2.5 mg, 50% of 10 study groups each.

Daily doseStudy groups
250 mcg to 500 mcg
5
500 mcg to 1 mg
0
1 mg to 2.5 mg
5

Dose per serving from research: Zinc

10 study groups in 7 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 50% of 10 study groups.

Daily doseStudy groups
5 mg to 10 mg
3
10 mg to 25 mg
5
25 mg to 50 mg
0
50 mg to 100 mg
2

Commonly used together

8 of 10 study groups took Copper and Zinc with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Iron
5

10 study groups

Study
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
2001 · Zinc · Adults aged 55–80 with age-related macular degeneration Categories 2–4 and visual acuity of 20/32 or better in at least one eye
2 mg80 mg8 years—
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
2001 · Antioxidants plus zinc · Adults aged 55–80 with age-related macular degeneration Categories 2–4 and visual acuity of 20/32 or better in at least one eye
2 mg80 mg8 years—
Micronutrient fortified milk improves iron status, anemia and growth among children 1-4 years: a double masked, randomized, controlled trial
2010 · Micronutrient-fortified milk (MN group) · Children aged 1–4 years in India; many had anemia, iron deficiency, or growth faltering
270 mcg7.8 mg1 year316
[Vitrum osteomag in prevention of osteoporosis in postmenopausal women: results of the comparative open multicenter trial]
2004 · Group 1: Vitrum Osteomag · Postmenopausal women with osteopenia; age range not reported
2 mg15 mg1 year125
Including 60 mg Elemental Iron in a Multiple Micronutrient Supplement Blunts the Increase in Serum Zinc after 12 Weeks of Daily Supplementation in Predominantly Anemic, Nonpregnant Cambodian Women of Reproductive Age
2019 · MMN · Predominantly anemic, nonpregnant women aged 18–45 years
2 mg15 mg12 weeks202
The effects of a lipid-based nutrient supplement and antiretroviral therapy in a randomized controlled trial on iron, copper, and zinc in milk from HIV-infected Malawian mothers and associations with maternal and infant biomarkers
2018 · LNS · HIV-infected lactating women in Malawi
300 mcg19 mg28 weeks185
Mineral status of non-anemic Peruvian infants taking an iron and copper syrup with or without zinc from 6 to 18 months of age: a randomized controlled trial
2013 · iron + copper + zinc group · Non-anemic Peruvian infants randomized at 6 months of age, born at term and weighing more than 2500 g; followed until 18 months
500 mcg10 mg1 year129
The effects of a lipid-based nutrient supplement and antiretroviral therapy in a randomized controlled trial on iron, copper, and zinc in milk from HIV-infected Malawian mothers and associations with maternal and infant biomarkers
2018 · ARV + LNS · HIV-infected lactating women in Malawi
300 mcg19 mg28 weeks90
Dose-response trial of prophylactic zinc supplements, with or without copper, in young Ecuadorian children at risk of zinc deficiency
2008 · 10 mg Zn + 0.5 mg Cu as copper sulfate · Ecuadorian children aged 12–30 months at baseline with length-for-age z scores below −1.3, at risk of zinc deficiency
500 mcg10 mg26 weeks—
Including 60 mg Elemental Iron in a Multiple Micronutrient Supplement Blunts the Increase in Serum Zinc after 12 Weeks of Daily Supplementation in Predominantly Anemic, Nonpregnant Cambodian Women of Reproductive Age
2019 · Fe + MMN · Predominantly anemic, nonpregnant women aged 18–45 years
2 mg15 mg12 weeks206