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Collagen and Vitamin C: study protocols

7 study groups took Collagen together with Vitamin C. These are the doses the studies gave. They are not a recommendation.

Collagen: what the research found →

Dose per serving from research: Collagen

7 study groups in 5 studies say how much Collagen participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 g to 5 g, 43% of 7 study groups.

Daily doseStudy groups
1 g to 2.5 g
2
2.5 g to 5 g
3
5 g to 10 g
0
10 g to 25 g
1
25 g to 50 g
1

Dose per serving from research: Vitamin C

5 study groups in 4 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg to 100 mg, 80% of 5 study groups.

Daily doseStudy groups
25 mg or less
1
25 mg to 50 mg
0
50 mg to 100 mg
4

Commonly used together

4 of 7 study groups took Collagen and Vitamin C with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin E
3

7 study groups

Study
The Sustained Effects of Bioactive Collagen Peptides on Skin Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
2025 · treated intervention group · Healthy women aged 35–55 years
5 g12.6 mg12 weeks41
The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled Trial
2024 · CP group · Healthy Caucasian women aged 40–65 years with skin ageing
5 g80 mg16 weeks30
The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled Trial
2024 · CPHA group · Healthy Caucasian women aged 40–65 years with skin ageing
5 g80 mg16 weeks30
A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study
2019 · verum group · Women aged 35–73 with healthy skin
2.5 g80 mg12 weeks36
A Dermonutrient Containing Special Collagen Peptides Improves Skin Structure and Function: A Randomized, Placebo-Controlled, Triple-Blind Trial Using Confocal Laser Scanning Microscopy on the Cosmetic Effects and Tolerance of a Drinkable Collagen Supplement
2020 · test product (Elasten) · Women aged 40–70 years; healthy, without a stated skin disease
2.5 g80 mg12 weeks30
Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis
2017 · 5 g gelatin group · Eight healthy adult men
15 g—3 days8
Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis
2017 · 15 g gelatin group · Eight healthy adult men
45 g—3 days8