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Beta-Carotene and Vitamin E: study protocols

36 study groups took Beta-Carotene together with Vitamin E. These are the doses the studies gave. They are not a recommendation.

Beta-Carotene: what the research found →

Dose per serving from research: Beta-Carotene

35 study groups in 26 studies say how much Beta-Carotene participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 66% of 35 study groups.

Daily doseStudy groups
5 mg to 10 mg
9
10 mg to 25 mg
23
25 mg to 50 mg
3

Dose per serving from research: Vitamin E

22 study groups in 20 studies say how much Vitamin E participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 82% of 22 study groups.

Daily doseStudy groups
10 mg to 25 mg
4
25 mg to 50 mg
18

Commonly used together

25 of 36 study groups took Beta-Carotene and Vitamin E with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin C
22
Zinc
14
Selenium
8

36 study groups

Study
The effect of alpha-tocopherol and beta-carotene supplementation on colorectal adenomas in middle-aged male smokers
1999 · both AT and BC · middle-aged male smokers
20 mg50 mg——
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
2001 · Antioxidants · Adults aged 55–80 with age-related macular degeneration Categories 2–4 and visual acuity of 20/32 or better in at least one eye
15 mg400 IU8 years—
Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13
2004 · antioxidants alone · Adults aged 55–81 years with age-related macular degeneration categories 1–4 or other AREDS ocular eligibility; participants in AMD categories 2–4 were eligible for this arm, and category 1 participants could also receive antioxidants
15 mg400 IU339 weeks—
Effect of alpha-tocopherol and beta-carotene supplementation on coronary heart disease during the 6-year post-trial follow-up in the ATBC study
2004 · alpha-tocopherol plus beta-carotene · men aged 50–69 who smoked
20 mg50 mg8 years—
Antioxidant vitamins supplementation and mortality: a randomized trial in head and neck cancer patients
2006 · supplement arm · Head and neck cancer patients treated by radiation therapy
30 mg400 IU——
Modification of the effect of vitamin E supplementation on the mortality of male smokers by age and dietary vitamin C
2009 · vitamin E + β-carotene · men aged 50–69 years who smoked at least 5 cigarettes per day
20 mg50 mg8 years—
Total and cancer mortality after supplementation with vitamins and minerals: follow-up of the Linxian General Population Nutrition Intervention Trial
2009 · Factor D · Adults in Linxian, China; age and sex details not given
15 mg30 mg313 weeks—
Associations between alpha-tocopherol, beta-carotene, and retinol and prostate cancer survival
2009 · α-tocopherol and β-carotene · Caucasian male smokers aged 50–69 years; prostate cancer cases were analysed in this report
20 mg50 mg8 years—
Vitamin E serum levels and controlled supplementation and risk of amyotrophic lateral sclerosis
2013 · combined β-carotene/α-tocopherol · Finnish male smokers aged 50–69
20 mg50 mg2227 days—
Long-term effects of vitamins C and E, β-carotene, and zinc on age-related macular degeneration: AREDS report no. 35
2013 · Antioxidants · Adults aged 55–80 with age-related macular degeneration (AREDS categories 1–4)
15 mg400 IU339 weeks—