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Beta-Carotene, Vitamin C and Zinc: study protocols

14 study groups took Beta-Carotene together with Vitamin C and Zinc. These are the doses the studies gave. They are not a recommendation.

Beta-Carotene: what the research found →

Dose per serving from research: Beta-Carotene

14 study groups in 12 studies say how much Beta-Carotene participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg and 10 mg to 25 mg, 50% of 14 study groups each.

Daily doseStudy groups
5 mg to 10 mg
7
10 mg to 25 mg
7

Dose per serving from research: Vitamin C

14 study groups in 12 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg and 250 mg to 500 mg, 50% of 14 study groups each.

Daily doseStudy groups
100 mg to 250 mg
7
250 mg to 500 mg
7

Dose per serving from research: Zinc

14 study groups in 12 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 57% of 14 study groups.

Daily doseStudy groups
10 mg to 25 mg
8
25 mg to 50 mg
0
50 mg to 100 mg
6

Commonly used together

14 of 14 study groups took Beta-Carotene, Vitamin C and Zinc with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin E
14
Selenium
7

14 study groups

Study
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
2001 · Antioxidants plus zinc · Adults aged 55–80 with age-related macular degeneration Categories 2–4 and visual acuity of 20/32 or better in at least one eye
15 mg500 mg80 mg8 years—
Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13
2004 · antioxidants plus zinc · Adults aged 55–81 years with AMD categories 2–4 and AREDS ocular eligibility
15 mg500 mg80 mg339 weeks—
The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals
2004 · antioxidant supplement group · French women aged 35–60 and men aged 45–60 in the general population
6 mg120 mg20 mg2739 days—
Antioxidant status and risk of cancer in the SU.VI.MAX study: is the effect of supplementation dependent on baseline levels?
2005 · daily antioxidant supplementation · French adults: women aged 35–60 years and men aged 45–60 years
6 mg120 mg20 mg2739 days—
Antioxidant supplementation increases the risk of skin cancers in women but not in men
2007 · antioxidant group · French adult women and men in a general-population primary-prevention trial
6 mg120 mg20 mg2738 days—
Long-term effects of vitamins C and E, β-carotene, and zinc on age-related macular degeneration: AREDS report no. 35
2013 · Antioxidants plus zinc · Adults aged 55–80 with age-related macular degeneration (AREDS categories 1–4)
15 mg500 mg80 mg339 weeks—
Effect of two years' supplementation with natural antioxidants on vitamin and trace element status biomarkers: preliminary data of the SU.VI.MAX study
2001 · Antioxidant supplementation group · Women aged 35–60 years and men aged 45–60 years in France, general population
6 mg120 mg20 mg2 years—
Effect of 6 month supplementation with different combinations of an association of antioxidant nutrients on biochemical parameters and markers of the antioxidant defence system in the elderly. The Geriatrie/Min.Vit.Aox Network
1996 · VT (vitamins associated with trace elements) · Elderly nursing-home residents aged 65–103 years who were long-term hospitalized
6 mg120 mg20 mg26 weeks—
Effects of trace element and/or vitamin supplementation on vitamin and mineral status, free radical metabolism and immunological markers in elderly long term-hospitalized subjects. Geriatric Network MIN. VIT. AOX
1997 · trace elements associated with vitamins · Institutionalized elderly subjects in long-term hospital or nursing-home care
6 mg120 mg20 mg1 year—
Effects of supplementation with a combination of antioxidant vitamins and trace elements, at nutritional doses, on biochemical indicators and markers of the antioxidant system in adult subjects
1998 · supplementation group · Adult men aged 45–60 years and women aged 35–60 years
6 mg120 mg20 mg26 weeks—