Alpha-Lipoic Acid and Vitamin C: study protocols
6 study groups took Alpha-Lipoic Acid together with Vitamin C. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Alpha-Lipoic Acid
6 study groups in 6 studies say how much Alpha-Lipoic Acid participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 500 mg to 1 g, 67% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 100 mg or less | 1 |
| 100 mg to 250 mg | 1 |
| 250 mg to 500 mg | 0 |
| 500 mg to 1 g | 4 |
Dose per serving from research: Vitamin C
6 study groups in 6 studies say how much Vitamin C participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 500 mg to 1 g, 67% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 100 mg to 250 mg | 1 |
| 250 mg to 500 mg | 1 |
| 500 mg to 1 g | 4 |
Commonly used together
6 of 6 study groups took Alpha-Lipoic Acid and Vitamin C with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Vitamin E | 4 |
6 study groups
| Study | ||||
|---|---|---|---|---|
| Acute mountain sickness; prophylactic benefits of antioxidant vitamin supplementation at high altitude 2001 · antioxidant group · Adults aged 35 ± 10 years ascending to high altitude; no diagnosed condition reported | 600 mg | 1 g | 31 days | 9 |
| Acute reversal of endothelial dysfunction in the elderly after antioxidant consumption 2012 · Antioxidant cocktail · Healthy young adults (mean age 25 ± 1 years) and older adults (mean age 71 ± 1 years), free of overt cardiovascular disease | 600 mg | 1 g | 1 day | 87 |
| Vascular dysfunction and chronic obstructive pulmonary disease: the role of redox balance 2014 · Antioxidant cocktail (AOC) · Adults: 30 patients with COPD and 30 age- and sex-matched controls | 600 mg | 1 g | 1 day | 60 |
| Effects of Macuprev(®) Supplementation in Age-Related Macular Degeneration: A Double-Blind Randomized Morpho-Functional Study Along 6 Months of Follow-Up 2019 · AMD-M group · Adults with intermediate age-related macular degeneration; 9 male and 21 female enrolled overall, mean age 69.32 years | 140 mg | 160 mg | 26 weeks | 15 |
| Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures 2012 · E/C/ALA · Adults aged 50–85 with probable Alzheimer disease and MMSE scores of 16 or more | 900 mg | 500 mg | 16 weeks | — |
| Plasma C-reactive protein concentrations in active and passive smokers: influence of antioxidant supplementation 2004 · antioxidant mixture · Healthy adult men and women who were active or passive smokers | 95 mg | 515 mg | 60 days | — |