Doctor's Best Milk Thistle Supplement, 120 Count

What the brand says

Milk thistle (silybum marianum) has been traditionally used in Europe as an herbal remedy for a variety of ailments, with a focus on conditions that affect liver health. Today, milk thistle dietary supplements are widely used in the USA And Europe by people concerned with liver health. The active compounds are commonly referred to collectively as sily marin (sometimes as flavonolignans) which actually refers to six structurally related compounds: silly bin a, b, isosilybin a, isosilybin b, silychristin and silydianin, as well as other minor polyphenolic compounds. Milk thistle seeds are 4 percent to 6 percent . Supplements typically contain a seed extract standardized to 80 percent content. Absorption after oral consumption is thought to be in the range of 20 to 50 percent. Once absorbed, the compounds undergo multiple conjugation reactions, i.e., metabolic modifications. Human pharmacokinetic studies report that the unmodified compounds and their sulfate and glucuronide conjugates can all be found circulating in the blood. The majority of excretion is thought to be via bile and from there into fecal excretion, as very little ends up in urine. Animal and human research results suggest that milk thistle extract has value for people with drug and alcohol induced liver damage, exposure to various environmental toxins. The beneficial mechanisms of milk thistle extract are thought to include antioxidant, immuno-modulatory, anti-fibrotic, anti-proliferative, anti-toxin and anti-viral properties.